Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer

One ofthe most common and troublesome complications ofmodern intensive anticancer treatments is oral mucositis. The purpose ofthis review is to summarize current evidente and clinical guidelines regarding its prevention and therapy. The use of keratinocyte growth factor-1, supplementary glutamine an...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ruiz-Esquide,Gonzalo, Nervi,Bruno, Vargas,Alex, Maíz,Alberto
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Antineoplastic protocols Cryotherapy Mucositis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300015
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872011000300015
record_format	dspace
spelling	oai:scielo:S0034-988720110003000152011-08-25Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncerRuiz-Esquide,GonzaloNervi,BrunoVargas,AlexMaíz,Alberto Antineoplastic protocols Cryotherapy Mucositis One ofthe most common and troublesome complications ofmodern intensive anticancer treatments is oral mucositis. The purpose ofthis review is to summarize current evidente and clinical guidelines regarding its prevention and therapy. The use of keratinocyte growth factor-1, supplementary glutamine and other recently developed treatment modalities are discussed. The injury ofthe oral mucosa caused by antineoplastic agents promotes the local expression of múltiple pro-inflammatory and pro-apoptotic molecules and eventually leads to the development of ulcers. Such lesions predispose patients to several infectious and nutritional complications. Also, they lead to modification of treatment schedules, potentially affecting overall prognosis. Local cryotherapy with ice chips and phototherapy with low energy láser may be useful as preventive measures. Mouthwashes with allopurinol and phototherapy with low energy láser can be used as treatment. In radiotherapy, special radiation administration techniques should be used to minimize mucosal injury. Pain control should always be optimized, with the use ofpatient controlled analgesia and topical use of morphine. Supplemental glutamine should not be used outside of research protocols. Lastly, thorough attention should bepaid to general care and hygiene measures.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.3 20112011-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300015es10.4067/S0034-98872011000300015
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antineoplastic protocols Cryotherapy Mucositis
spellingShingle	Antineoplastic protocols Cryotherapy Mucositis Ruiz-Esquide,Gonzalo Nervi,Bruno Vargas,Alex Maíz,Alberto Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
description	One ofthe most common and troublesome complications ofmodern intensive anticancer treatments is oral mucositis. The purpose ofthis review is to summarize current evidente and clinical guidelines regarding its prevention and therapy. The use of keratinocyte growth factor-1, supplementary glutamine and other recently developed treatment modalities are discussed. The injury ofthe oral mucosa caused by antineoplastic agents promotes the local expression of múltiple pro-inflammatory and pro-apoptotic molecules and eventually leads to the development of ulcers. Such lesions predispose patients to several infectious and nutritional complications. Also, they lead to modification of treatment schedules, potentially affecting overall prognosis. Local cryotherapy with ice chips and phototherapy with low energy láser may be useful as preventive measures. Mouthwashes with allopurinol and phototherapy with low energy láser can be used as treatment. In radiotherapy, special radiation administration techniques should be used to minimize mucosal injury. Pain control should always be optimized, with the use ofpatient controlled analgesia and topical use of morphine. Supplemental glutamine should not be used outside of research protocols. Lastly, thorough attention should bepaid to general care and hygiene measures.
author	Ruiz-Esquide,Gonzalo Nervi,Bruno Vargas,Alex Maíz,Alberto
author_facet	Ruiz-Esquide,Gonzalo Nervi,Bruno Vargas,Alex Maíz,Alberto
author_sort	Ruiz-Esquide,Gonzalo
title	Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
title_short	Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
title_full	Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
title_fullStr	Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
title_full_unstemmed	Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
title_sort	tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300015
work_keys_str_mv	AT ruizesquidegonzalo tratamientoyprevenciondelamucositisoralasociadaaltratamientodelcancer AT nervibruno tratamientoyprevenciondelamucositisoralasociadaaltratamientodelcancer AT vargasalex tratamientoyprevenciondelamucositisoralasociadaaltratamientodelcancer AT maizalberto tratamientoyprevenciondelamucositisoralasociadaaltratamientodelcancer
_version_	1718436558411923456

Tratamiento y prevención de la mucositis oral asociada al tratamiento del cáncer

Ejemplares similares