Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos

Background: The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis. Aim: To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma. Material and Methods: Rev...

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Autores principales: Tapia E,Oscar, Villaseca H,Miguel, Bellolio J,Enrique, Araya O,Juan Carlos, Roa S,Juan Carlos
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000400003
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spelling oai:scielo:S0034-988720110004000032011-08-25Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticosTapia E,OscarVillaseca H,MiguelBellolio J,EnriqueAraya O,Juan CarlosRoa S,Juan Carlos Gastrectomy Risk factors Stomach neoplasms Survival Background: The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis. Aim: To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma. Material and Methods: Review of pathologica records of a regional general hospital, identifying patients with a N0 gastric cancer surgically excised between 1986 and 2003. Results: In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement. These later patients were followed for a median of 64 months with a 71% fve years actuarial survival. Bivariate analysis identifed age, tumor size, gastric wallinfiltration, pathological type according to Lauren and Ming, lymphovascular involvement, number of lymph nodes excised and TNM stage as prognostic values Multivariate analysis disclosed the level of gastric wallinfiltration, the presence of a poorly differentiated tumor, lymphatic vascular involvement, number of excise lymph nodes and tumor size as independent prognostic factors. Conclusions: N0 gastric tumors are found in 32% of gastrectomies for gastric cancer and have a 71% fve years actuarial survival. Gastric wallinfiltration, pathological degree of differentiation tumor size and lymphovascular involvement are independent prognostic factors.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.4 20112011-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000400003es10.4067/S0034-98872011000400003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Gastrectomy
Risk factors
Stomach neoplasms
Survival
spellingShingle Gastrectomy
Risk factors
Stomach neoplasms
Survival
Tapia E,Oscar
Villaseca H,Miguel
Bellolio J,Enrique
Araya O,Juan Carlos
Roa S,Juan Carlos
Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos
description Background: The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis. Aim: To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma. Material and Methods: Review of pathologica records of a regional general hospital, identifying patients with a N0 gastric cancer surgically excised between 1986 and 2003. Results: In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement. These later patients were followed for a median of 64 months with a 71% fve years actuarial survival. Bivariate analysis identifed age, tumor size, gastric wallinfiltration, pathological type according to Lauren and Ming, lymphovascular involvement, number of lymph nodes excised and TNM stage as prognostic values Multivariate analysis disclosed the level of gastric wallinfiltration, the presence of a poorly differentiated tumor, lymphatic vascular involvement, number of excise lymph nodes and tumor size as independent prognostic factors. Conclusions: N0 gastric tumors are found in 32% of gastrectomies for gastric cancer and have a 71% fve years actuarial survival. Gastric wallinfiltration, pathological degree of differentiation tumor size and lymphovascular involvement are independent prognostic factors.
author Tapia E,Oscar
Villaseca H,Miguel
Bellolio J,Enrique
Araya O,Juan Carlos
Roa S,Juan Carlos
author_facet Tapia E,Oscar
Villaseca H,Miguel
Bellolio J,Enrique
Araya O,Juan Carlos
Roa S,Juan Carlos
author_sort Tapia E,Oscar
title Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos
title_short Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos
title_full Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos
title_fullStr Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos
title_full_unstemmed Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos
title_sort cáncer gástrico sin compromiso ganglionar linfático (pn0): características demográfico-patológicas y factores pronósticos
publisher Sociedad Médica de Santiago
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000400003
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