Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche

Background: Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. Aim: To determine the source of Pertussis infection in infants aged six months or less in Chile. Material and Methods: Twenty six household contacts of 10 youn...

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Autores principales:	Perret,Cecilia, Viviani,Tamara, Peña,Anamaría, Abarca,Katia, Ferrés,Marcela
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Bordetella pertussis Infant Risk factors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000400005
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spelling	oai:scielo:S0034-988720110004000052011-08-25Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluchePerret,CeciliaViviani,TamaraPeña,AnamaríaAbarca,KatiaFerrés,Marcela Bordetella pertussis Infant Risk factors Background: Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. Aim: To determine the source of Pertussis infection in infants aged six months or less in Chile. Material and Methods: Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polyme-rase chain reaction (PCR). Clinical and demographic data were analyzed. Results: Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identifed in every household and in 18 (72%) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identifed in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR. Conclusions: B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.4 20112011-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000400005es10.4067/S0034-98872011000400005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Bordetella pertussis Infant Risk factors
spellingShingle	Bordetella pertussis Infant Risk factors Perret,Cecilia Viviani,Tamara Peña,Anamaría Abarca,Katia Ferrés,Marcela Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
description	Background: Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. Aim: To determine the source of Pertussis infection in infants aged six months or less in Chile. Material and Methods: Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polyme-rase chain reaction (PCR). Clinical and demographic data were analyzed. Results: Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identifed in every household and in 18 (72%) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identifed in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR. Conclusions: B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants.
author	Perret,Cecilia Viviani,Tamara Peña,Anamaría Abarca,Katia Ferrés,Marcela
author_facet	Perret,Cecilia Viviani,Tamara Peña,Anamaría Abarca,Katia Ferrés,Marcela
author_sort	Perret,Cecilia
title	Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
title_short	Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
title_full	Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
title_fullStr	Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
title_full_unstemmed	Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
title_sort	fuente de infección de bordetella pertussis en lactantes hospitalizados por coqueluche
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000400005
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Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche

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