Aterosclerosis en sujetos con periodontitis

Background: Chronic infl ammation and infections are involved in the development and progression of atherosclerotic vascular disease. Aim: To evaluate the association between periodontitis and early atherosclerosis. Material and Methods: Fifty-three subjects who received periodontal treatment and re...

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Autores principales:	López,Néstor J, Chamorro,Adriana, Llancaqueo,Marcelo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Atherosclerosis Periodontitis Risk factors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000600004
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spelling	oai:scielo:S0034-988720110006000042011-09-14Aterosclerosis en sujetos con periodontitisLópez,Néstor JChamorro,AdrianaLlancaqueo,Marcelo Atherosclerosis Periodontitis Risk factors Background: Chronic infl ammation and infections are involved in the development and progression of atherosclerotic vascular disease. Aim: To evaluate the association between periodontitis and early atherosclerosis. Material and Methods: Fifty-three subjects who received periodontal treatment and regular maintenance for at least 10 years, and 55 subjects with periodontitis but without a history of periodontal treatment were studied. Carotid artery intima-media wall thickness (CIMT) was measured with high-resolution B-mode ultrasonography. A blood sample was obtained to measure high sensitivity C-reactive protein, fibrinogen, lipoprotein cholesterol, leukocyte count and erythrocyte sedimentation rate. Covariates included age, gender, smoking, level of education, body mass index and physical activity. The benzoyl-DL-arginine-naphthylamide (BANA) test was used to determine the number of periodontal sites with periodontal pathogens. Results: CIMT value was significantly higher in subjects with periodontitis than those without it (0.775 ± 0.268 and 0.683 ± 0.131 mm respectively, p = 0.027). C-reactive protein, leukocyte count and percentage of sites with periodontal pathogens were also significantly higher in subjects with periodontitis. Regression analysis identified age, periodontitis, and smoking as independent predictors of CIMT. Conclusions: These results suggest that untreated periodontitis is associated with early atherosclerotic carotid lesions and higher levels of infl ammatory markers.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.6 20112011-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000600004es10.4067/S0034-98872011000600004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Atherosclerosis Periodontitis Risk factors
spellingShingle	Atherosclerosis Periodontitis Risk factors López,Néstor J Chamorro,Adriana Llancaqueo,Marcelo Aterosclerosis en sujetos con periodontitis
description	Background: Chronic infl ammation and infections are involved in the development and progression of atherosclerotic vascular disease. Aim: To evaluate the association between periodontitis and early atherosclerosis. Material and Methods: Fifty-three subjects who received periodontal treatment and regular maintenance for at least 10 years, and 55 subjects with periodontitis but without a history of periodontal treatment were studied. Carotid artery intima-media wall thickness (CIMT) was measured with high-resolution B-mode ultrasonography. A blood sample was obtained to measure high sensitivity C-reactive protein, fibrinogen, lipoprotein cholesterol, leukocyte count and erythrocyte sedimentation rate. Covariates included age, gender, smoking, level of education, body mass index and physical activity. The benzoyl-DL-arginine-naphthylamide (BANA) test was used to determine the number of periodontal sites with periodontal pathogens. Results: CIMT value was significantly higher in subjects with periodontitis than those without it (0.775 ± 0.268 and 0.683 ± 0.131 mm respectively, p = 0.027). C-reactive protein, leukocyte count and percentage of sites with periodontal pathogens were also significantly higher in subjects with periodontitis. Regression analysis identified age, periodontitis, and smoking as independent predictors of CIMT. Conclusions: These results suggest that untreated periodontitis is associated with early atherosclerotic carotid lesions and higher levels of infl ammatory markers.
author	López,Néstor J Chamorro,Adriana Llancaqueo,Marcelo
author_facet	López,Néstor J Chamorro,Adriana Llancaqueo,Marcelo
author_sort	López,Néstor J
title	Aterosclerosis en sujetos con periodontitis
title_short	Aterosclerosis en sujetos con periodontitis
title_full	Aterosclerosis en sujetos con periodontitis
title_fullStr	Aterosclerosis en sujetos con periodontitis
title_full_unstemmed	Aterosclerosis en sujetos con periodontitis
title_sort	aterosclerosis en sujetos con periodontitis
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000600004
work_keys_str_mv	AT lopeznestorj aterosclerosisensujetosconperiodontitis AT chamorroadriana aterosclerosisensujetosconperiodontitis AT llancaqueomarcelo aterosclerosisensujetosconperiodontitis
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Aterosclerosis en sujetos con periodontitis

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