Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor

Patients on immunosuppressive therapy are at increased risk of developing tuberculosis. We report a 39-year-old female with an ulcerative colitis receiving prednisone, azathioprine and azulfidine that was admitted to hospital due to fever, anemia, diarrhea and hematochezia. A chest CT scan showed mu...

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Autores principales:	Silva,Rafael, Jara,Juan, Soto,Tulio, Sepúlveda,Pedro
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Methylprednisolone Shock septic Tuberculosis miliary
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000600012
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spelling	oai:scielo:S0034-988720110006000122011-09-14Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresorSilva,RafaelJara,JuanSoto,TulioSepúlveda,Pedro Methylprednisolone Shock septic Tuberculosis miliary Patients on immunosuppressive therapy are at increased risk of developing tuberculosis. We report a 39-year-old female with an ulcerative colitis receiving prednisone, azathioprine and azulfidine that was admitted to hospital due to fever, anemia, diarrhea and hematochezia. A chest CT scan showed multiple miliary micronodular images diffusely distributed and mediastinal enlarged lymph nodes with central necrosis, suggestive of disseminated tuberculosis. Antituberculous treatment was started but discontinued and the patient was treated as a bronchiolitis obliterans with methylprednisolone pulses and discharged. She was readmitted in shock one week later and died. After her death cultures for Mycobacterium tuberculosis were informed as positive. The clinical picture of the patient is known as sepsis tuberculosa gravissima.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.6 20112011-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000600012es10.4067/S0034-98872011000600012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Methylprednisolone Shock septic Tuberculosis miliary
spellingShingle	Methylprednisolone Shock septic Tuberculosis miliary Silva,Rafael Jara,Juan Soto,Tulio Sepúlveda,Pedro Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor
description	Patients on immunosuppressive therapy are at increased risk of developing tuberculosis. We report a 39-year-old female with an ulcerative colitis receiving prednisone, azathioprine and azulfidine that was admitted to hospital due to fever, anemia, diarrhea and hematochezia. A chest CT scan showed multiple miliary micronodular images diffusely distributed and mediastinal enlarged lymph nodes with central necrosis, suggestive of disseminated tuberculosis. Antituberculous treatment was started but discontinued and the patient was treated as a bronchiolitis obliterans with methylprednisolone pulses and discharged. She was readmitted in shock one week later and died. After her death cultures for Mycobacterium tuberculosis were informed as positive. The clinical picture of the patient is known as sepsis tuberculosa gravissima.
author	Silva,Rafael Jara,Juan Soto,Tulio Sepúlveda,Pedro
author_facet	Silva,Rafael Jara,Juan Soto,Tulio Sepúlveda,Pedro
author_sort	Silva,Rafael
title	Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor
title_short	Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor
title_full	Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor
title_fullStr	Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor
title_full_unstemmed	Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor
title_sort	sepsis tuberculosa gravissima: una presentación infrecuente en paciente con tratamiento inmunosupresor
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000600012
work_keys_str_mv	AT silvarafael sepsistuberculosagravissimaunapresentacioninfrecuenteenpacientecontratamientoinmunosupresor AT jarajuan sepsistuberculosagravissimaunapresentacioninfrecuenteenpacientecontratamientoinmunosupresor AT sototulio sepsistuberculosagravissimaunapresentacioninfrecuenteenpacientecontratamientoinmunosupresor AT sepulvedapedro sepsistuberculosagravissimaunapresentacioninfrecuenteenpacientecontratamientoinmunosupresor
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Sepsis tuberculosa gravissima: Una presentación infrecuente en paciente con tratamiento inmunosupresor

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