La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria

Background: Patients who develop hyponatremia during their hospitalization have higher hospital mortality. Aim: To determine if the presence of hyponatremia on admission to the emergency room is a risk factor for hospital mortality. Patients and Methods: Two hundred forty five patients consecutively...

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Autores principales:	Vega,Jorge, Manríquez,Francisco, Madrid,Eva, Goecke,Helmuth, Carrasco,Alejandra, Martínez,Gonzalo, Joyas,Alejandro, Rojas,Fernando, Salinas,Julio, Borja,Hernán
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Emergency Service hospital Hospital mortality Hyponatremia
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800002
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spelling	oai:scielo:S0034-988720110008000022011-12-20La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalariaVega,JorgeManríquez,FranciscoMadrid,EvaGoecke,HelmuthCarrasco,AlejandraMartínez,GonzaloJoyas,AlejandroRojas,FernandoSalinas,JulioBorja,Hernán Emergency Service hospital Hospital mortality Hyponatremia Background: Patients who develop hyponatremia during their hospitalization have higher hospital mortality. Aim: To determine if the presence of hyponatremia on admission to the emergency room is a risk factor for hospital mortality. Patients and Methods: Two hundred forty five patients consecutively admitted to the emergency room and then transferred to the Medicine Department, where they finally died, were matched for age and gender with 245 control subjects admitted to the emergency room and hospitalized in the Medicine Department at the same time, but survived. The dependent variable was death, and the exposure variable was hyponatremia. Admission diagnosis and Charlson comorbidity index was considered as confounding variables. Results: Hyponatremia at admission occurred in 30 and 17% of patients who died and survived, respectively, rendering an adjusted odds ratio for death of 2.13 (95% confidence intervals = 1.27-3.57). Charlson Comorbidity Index according to age score was higher in subjects with hyponatremia compared to those without hyponatremia (8.1 ± 3.1 and 7.2 ± 2.8; p = 0.01). Multivariate analysis showed that age, gender, length of stay, cause of hospitalization and chronic diseases did not significantly modify the effect of hyponatremia on hospital mortality. Conclusions: Hyponatremia on admission at emergency room had a significant association with hospital mortality. Subjects with hyponatremia had a higher Charlson Comorbidity Index score.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.8 20112011-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800002es10.4067/S0034-98872011000800002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Emergency Service hospital Hospital mortality Hyponatremia
spellingShingle	Emergency Service hospital Hospital mortality Hyponatremia Vega,Jorge Manríquez,Francisco Madrid,Eva Goecke,Helmuth Carrasco,Alejandra Martínez,Gonzalo Joyas,Alejandro Rojas,Fernando Salinas,Julio Borja,Hernán La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
description	Background: Patients who develop hyponatremia during their hospitalization have higher hospital mortality. Aim: To determine if the presence of hyponatremia on admission to the emergency room is a risk factor for hospital mortality. Patients and Methods: Two hundred forty five patients consecutively admitted to the emergency room and then transferred to the Medicine Department, where they finally died, were matched for age and gender with 245 control subjects admitted to the emergency room and hospitalized in the Medicine Department at the same time, but survived. The dependent variable was death, and the exposure variable was hyponatremia. Admission diagnosis and Charlson comorbidity index was considered as confounding variables. Results: Hyponatremia at admission occurred in 30 and 17% of patients who died and survived, respectively, rendering an adjusted odds ratio for death of 2.13 (95% confidence intervals = 1.27-3.57). Charlson Comorbidity Index according to age score was higher in subjects with hyponatremia compared to those without hyponatremia (8.1 ± 3.1 and 7.2 ± 2.8; p = 0.01). Multivariate analysis showed that age, gender, length of stay, cause of hospitalization and chronic diseases did not significantly modify the effect of hyponatremia on hospital mortality. Conclusions: Hyponatremia on admission at emergency room had a significant association with hospital mortality. Subjects with hyponatremia had a higher Charlson Comorbidity Index score.
author	Vega,Jorge Manríquez,Francisco Madrid,Eva Goecke,Helmuth Carrasco,Alejandra Martínez,Gonzalo Joyas,Alejandro Rojas,Fernando Salinas,Julio Borja,Hernán
author_facet	Vega,Jorge Manríquez,Francisco Madrid,Eva Goecke,Helmuth Carrasco,Alejandra Martínez,Gonzalo Joyas,Alejandro Rojas,Fernando Salinas,Julio Borja,Hernán
author_sort	Vega,Jorge
title	La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
title_short	La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
title_full	La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
title_fullStr	La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
title_full_unstemmed	La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
title_sort	la hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800002
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La hiponatremia al momento de ingreso como factor de riesgo de mortalidad hospitalaria

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