Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico

Background: Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim: To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and su...

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Autores principales: Tapia E,Oscar, Villaseca H,Miguel, Araya O,Juan Carlos, Roa S,Juan Carlos
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800003
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spelling oai:scielo:S0034-988720110008000032011-12-20Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronósticoTapia E,OscarVillaseca H,MiguelAraya O,Juan CarlosRoa S,Juan Carlos Lymph nodes Prognosis Stomach neoplasms Background: Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim: To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and survival of patients with gastric cancer and lymph node involvement operated between 1986 and 2003, were analyzed. Patients with and without extracapsular involvement were compared. Results: During the study period, 459 gastrectomies were performed, 312 patients (68%) had lymph node involvement and 144 (31%) had extracapsular involvement. Patients with and without extracapsular involvement were followed for a median of 10 (range 1 to 120) and 41 (range 1 to 193) months, respectively. Five years actuarial survival for patients with and without extracapsular involvement was 23 and 40% respectively. Extracapsular lymph node involvement and level of wall infiltration were identified as prognostic factors using a multivariate analysis. Conclusions: Extracapsular lymph node involvement is an independent risk factor for mortality among patients with gastric cancer.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.8 20112011-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800003es10.4067/S0034-98872011000800003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Lymph nodes
Prognosis
Stomach neoplasms
spellingShingle Lymph nodes
Prognosis
Stomach neoplasms
Tapia E,Oscar
Villaseca H,Miguel
Araya O,Juan Carlos
Roa S,Juan Carlos
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
description Background: Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim: To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and survival of patients with gastric cancer and lymph node involvement operated between 1986 and 2003, were analyzed. Patients with and without extracapsular involvement were compared. Results: During the study period, 459 gastrectomies were performed, 312 patients (68%) had lymph node involvement and 144 (31%) had extracapsular involvement. Patients with and without extracapsular involvement were followed for a median of 10 (range 1 to 120) and 41 (range 1 to 193) months, respectively. Five years actuarial survival for patients with and without extracapsular involvement was 23 and 40% respectively. Extracapsular lymph node involvement and level of wall infiltration were identified as prognostic factors using a multivariate analysis. Conclusions: Extracapsular lymph node involvement is an independent risk factor for mortality among patients with gastric cancer.
author Tapia E,Oscar
Villaseca H,Miguel
Araya O,Juan Carlos
Roa S,Juan Carlos
author_facet Tapia E,Oscar
Villaseca H,Miguel
Araya O,Juan Carlos
Roa S,Juan Carlos
author_sort Tapia E,Oscar
title Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
title_short Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
title_full Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
title_fullStr Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
title_full_unstemmed Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
title_sort compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
publisher Sociedad Médica de Santiago
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800003
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AT villasecahmiguel compromisoganglionarextracapsularenpacientesconcancergastricodeterminaciondelvalorpronostico
AT arayaojuancarlos compromisoganglionarextracapsularenpacientesconcancergastricodeterminaciondelvalorpronostico
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