Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico
Background: Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim: To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and su...
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Sociedad Médica de Santiago
2011
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oai:scielo:S0034-988720110008000032011-12-20Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronósticoTapia E,OscarVillaseca H,MiguelAraya O,Juan CarlosRoa S,Juan Carlos Lymph nodes Prognosis Stomach neoplasms Background: Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim: To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and survival of patients with gastric cancer and lymph node involvement operated between 1986 and 2003, were analyzed. Patients with and without extracapsular involvement were compared. Results: During the study period, 459 gastrectomies were performed, 312 patients (68%) had lymph node involvement and 144 (31%) had extracapsular involvement. Patients with and without extracapsular involvement were followed for a median of 10 (range 1 to 120) and 41 (range 1 to 193) months, respectively. Five years actuarial survival for patients with and without extracapsular involvement was 23 and 40% respectively. Extracapsular lymph node involvement and level of wall infiltration were identified as prognostic factors using a multivariate analysis. Conclusions: Extracapsular lymph node involvement is an independent risk factor for mortality among patients with gastric cancer.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.8 20112011-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800003es10.4067/S0034-98872011000800003 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Lymph nodes Prognosis Stomach neoplasms |
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Lymph nodes Prognosis Stomach neoplasms Tapia E,Oscar Villaseca H,Miguel Araya O,Juan Carlos Roa S,Juan Carlos Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
description |
Background: Extracapsular lymph node involvement has a negative prognosis in malignant tumors. Aim: To assess the prognostic importance of extracapsular lymph node involvement in patients with gastric cancer with lymph node metastases. Material and Methods: Clinical and morphological features and survival of patients with gastric cancer and lymph node involvement operated between 1986 and 2003, were analyzed. Patients with and without extracapsular involvement were compared. Results: During the study period, 459 gastrectomies were performed, 312 patients (68%) had lymph node involvement and 144 (31%) had extracapsular involvement. Patients with and without extracapsular involvement were followed for a median of 10 (range 1 to 120) and 41 (range 1 to 193) months, respectively. Five years actuarial survival for patients with and without extracapsular involvement was 23 and 40% respectively. Extracapsular lymph node involvement and level of wall infiltration were identified as prognostic factors using a multivariate analysis. Conclusions: Extracapsular lymph node involvement is an independent risk factor for mortality among patients with gastric cancer. |
author |
Tapia E,Oscar Villaseca H,Miguel Araya O,Juan Carlos Roa S,Juan Carlos |
author_facet |
Tapia E,Oscar Villaseca H,Miguel Araya O,Juan Carlos Roa S,Juan Carlos |
author_sort |
Tapia E,Oscar |
title |
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
title_short |
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
title_full |
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
title_fullStr |
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
title_full_unstemmed |
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
title_sort |
compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico |
publisher |
Sociedad Médica de Santiago |
publishDate |
2011 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000800003 |
work_keys_str_mv |
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