Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile

Background: The only accepted treatment for acute ischemic stroke is thrombolysis with recombinant tissue plasminogen activator (t-PA). It was implemented in Chile in 1996, although its use was mainly restricted in Chile to private clinics. Recently, at year 2009, we have implemented this treatment...

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Autores principales:	Figueroa-Reyes,Tatiana, Sáez M,David, Mansilla L,Eloy, Sánchez V,Rodrigo, Nogales-Gaete,Jorge, Delgado B,Iris
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Plasminogen activators Stroke Thrombolytic therapy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000900002
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spelling	oai:scielo:S0034-988720110009000022011-11-17Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de ChileFigueroa-Reyes,TatianaSáez M,DavidMansilla L,EloySánchez V,RodrigoNogales-Gaete,JorgeDelgado B,Iris Plasminogen activators Stroke Thrombolytic therapy Background: The only accepted treatment for acute ischemic stroke is thrombolysis with recombinant tissue plasminogen activator (t-PA). It was implemented in Chile in 1996, although its use was mainly restricted in Chile to private clinics. Recently, at year 2009, we have implemented this treatment in a public hospital. Aim: To describe the results of treatment of acute ischemic stroke with t-PA in a public hospital in Chile. Material and Methods: Prospective analysis of all eligible patients with acute ischemic stroke that were admitted within 4 hours of its onset and had no contraindications for thrombolysis. Results: In an eight months period, a total of 19 intravenous thrombolyses were performed in 12 males and seven females aged 28 to 79 years old. The mean lapse between onset of symptoms and onset of thrombolysis was 190 ± 57 min. Results were favorable, according to Rankin and National Institute of Health Stroke scales. Ninety days after treatment, 63% of patients had minimal or absent disability, 26% had moderate disability and only one (5%) had severe disability. One patient had a clinically not significant intracranial hemorrhage and one patient died six days after thrombolysis. Conclusions: These results indicate that thrombolysis can be successfully implemented in Chilean public hospitals. The limitations for its use in this setting are mostly administrative.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.9 20112011-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000900002es10.4067/S0034-98872011000900002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Plasminogen activators Stroke Thrombolytic therapy
spellingShingle	Plasminogen activators Stroke Thrombolytic therapy Figueroa-Reyes,Tatiana Sáez M,David Mansilla L,Eloy Sánchez V,Rodrigo Nogales-Gaete,Jorge Delgado B,Iris Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
description	Background: The only accepted treatment for acute ischemic stroke is thrombolysis with recombinant tissue plasminogen activator (t-PA). It was implemented in Chile in 1996, although its use was mainly restricted in Chile to private clinics. Recently, at year 2009, we have implemented this treatment in a public hospital. Aim: To describe the results of treatment of acute ischemic stroke with t-PA in a public hospital in Chile. Material and Methods: Prospective analysis of all eligible patients with acute ischemic stroke that were admitted within 4 hours of its onset and had no contraindications for thrombolysis. Results: In an eight months period, a total of 19 intravenous thrombolyses were performed in 12 males and seven females aged 28 to 79 years old. The mean lapse between onset of symptoms and onset of thrombolysis was 190 ± 57 min. Results were favorable, according to Rankin and National Institute of Health Stroke scales. Ninety days after treatment, 63% of patients had minimal or absent disability, 26% had moderate disability and only one (5%) had severe disability. One patient had a clinically not significant intracranial hemorrhage and one patient died six days after thrombolysis. Conclusions: These results indicate that thrombolysis can be successfully implemented in Chilean public hospitals. The limitations for its use in this setting are mostly administrative.
author	Figueroa-Reyes,Tatiana Sáez M,David Mansilla L,Eloy Sánchez V,Rodrigo Nogales-Gaete,Jorge Delgado B,Iris
author_facet	Figueroa-Reyes,Tatiana Sáez M,David Mansilla L,Eloy Sánchez V,Rodrigo Nogales-Gaete,Jorge Delgado B,Iris
author_sort	Figueroa-Reyes,Tatiana
title	Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
title_short	Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
title_full	Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
title_fullStr	Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
title_full_unstemmed	Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
title_sort	experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de chile
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000900002
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Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile

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