Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré

Adverse reactions to intravenous immunoglobulin (ivIg) therapy, such as anaphylaxis, acute encephalopathy, aseptic meningitis, or thrombotic phenomena are uncommon. We report a 58-year-old man with hypertension presenting with muscle weakness which led to paraparesia and respiratory failure. With th...

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Autores principales: Soto V,Álvaro, Cartier R,Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001000014
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spelling oai:scielo:S0034-988720110010000142012-01-03Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-BarréSoto V,ÁlvaroCartier R,Luis Guillain-Barré syndrome Immunoglobulin intravenous Neurotoxicity syndromes Adverse reactions to intravenous immunoglobulin (ivIg) therapy, such as anaphylaxis, acute encephalopathy, aseptic meningitis, or thrombotic phenomena are uncommon. We report a 58-year-old man with hypertension presenting with muscle weakness which led to paraparesia and respiratory failure. With the diagnosis of Guillain-Barré syndrome (GBS), he was treated with ivIg. He developed an acute encephalopathy few hours after the administration of ivIg, with a decreased level of consciousness and agitation. A CT scan revealed moderate and diffuse brain edema. Encephalopathy resolved 96 hours after ivIg withdrawal and use of plasma exchange. A CT scan performed seven days after showed the resolution of brain edema.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.10 20112011-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001000014es10.4067/S0034-98872011001000014
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Guillain-Barré syndrome
Immunoglobulin intravenous
Neurotoxicity syndromes
spellingShingle Guillain-Barré syndrome
Immunoglobulin intravenous
Neurotoxicity syndromes
Soto V,Álvaro
Cartier R,Luis
Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré
description Adverse reactions to intravenous immunoglobulin (ivIg) therapy, such as anaphylaxis, acute encephalopathy, aseptic meningitis, or thrombotic phenomena are uncommon. We report a 58-year-old man with hypertension presenting with muscle weakness which led to paraparesia and respiratory failure. With the diagnosis of Guillain-Barré syndrome (GBS), he was treated with ivIg. He developed an acute encephalopathy few hours after the administration of ivIg, with a decreased level of consciousness and agitation. A CT scan revealed moderate and diffuse brain edema. Encephalopathy resolved 96 hours after ivIg withdrawal and use of plasma exchange. A CT scan performed seven days after showed the resolution of brain edema.
author Soto V,Álvaro
Cartier R,Luis
author_facet Soto V,Álvaro
Cartier R,Luis
author_sort Soto V,Álvaro
title Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré
title_short Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré
title_full Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré
title_fullStr Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré
title_full_unstemmed Encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de Guillain-Barré
title_sort encefalopatía aguda en un paciente tratado con inmunoglobulina endovenosa por un síndrome de guillain-barré
publisher Sociedad Médica de Santiago
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001000014
work_keys_str_mv AT sotovalvaro encefalopatiaagudaenunpacientetratadoconinmunoglobulinaendovenosaporunsindromedeguillainbarre
AT cartierrluis encefalopatiaagudaenunpacientetratadoconinmunoglobulinaendovenosaporunsindromedeguillainbarre
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