Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años

Background: Inflammatory bowel disease (IBD) has a peak incidence between 15 and 25 years of age, thereby affecting women of reproductive age. Fertility rates with inactive IBD are similar to the general population, and drugs currently used, with the exception of methotrexate and thalidomide, have a...

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Autores principales: Vergara A,María Teresa, Rey G,Paula
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100005
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spelling oai:scielo:S0034-988720110011000052012-02-08Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 añosVergara A,María TeresaRey G,Paula Delivery obstetric Inflammatory bowel diseases Pregnancy complications Background: Inflammatory bowel disease (IBD) has a peak incidence between 15 and 25 years of age, thereby affecting women of reproductive age. Fertility rates with inactive IBD are similar to the general population, and drugs currently used, with the exception of methotrexate and thalidomide, have a good safety and efficacy profile during pregnancy. Starting a pregnancy with inactive IBD significantly reduces the potential maternal and fetal complications. Aim: To assess the evolution of pregnancy and the underlying disease in women with IBD. Patients and Methods: Retrospective and prospective study of female patients with IBD controlled in our hospital who became pregnant from January 1994 to February, 2011. Results: We followed 17patients with a total of 19 pregnancies. In two patients the onset of IBD occurred during pregnancy and from the remaining, 11 patients became pregnant during remission of IBD. Most of the patients continued the same treatment during pregnancy and the few flares that occurred were treated satisfactorily. Major complications occurred in three patients, all associated with IBD activity. Fifteen patients had full-term deliveries and the majority of the newborns had normal weight and Apgar score. None had malformations. Conclusions: Pregnancies among patients with an inactive IBD, have a good evolution. A multidisciplinary approach and patient education are invaluable to achieve these good results.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.11 20112011-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100005es10.4067/S0034-98872011001100005
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Delivery
obstetric
Inflammatory bowel diseases
Pregnancy complications
spellingShingle Delivery
obstetric
Inflammatory bowel diseases
Pregnancy complications
Vergara A,María Teresa
Rey G,Paula
Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
description Background: Inflammatory bowel disease (IBD) has a peak incidence between 15 and 25 years of age, thereby affecting women of reproductive age. Fertility rates with inactive IBD are similar to the general population, and drugs currently used, with the exception of methotrexate and thalidomide, have a good safety and efficacy profile during pregnancy. Starting a pregnancy with inactive IBD significantly reduces the potential maternal and fetal complications. Aim: To assess the evolution of pregnancy and the underlying disease in women with IBD. Patients and Methods: Retrospective and prospective study of female patients with IBD controlled in our hospital who became pregnant from January 1994 to February, 2011. Results: We followed 17patients with a total of 19 pregnancies. In two patients the onset of IBD occurred during pregnancy and from the remaining, 11 patients became pregnant during remission of IBD. Most of the patients continued the same treatment during pregnancy and the few flares that occurred were treated satisfactorily. Major complications occurred in three patients, all associated with IBD activity. Fifteen patients had full-term deliveries and the majority of the newborns had normal weight and Apgar score. None had malformations. Conclusions: Pregnancies among patients with an inactive IBD, have a good evolution. A multidisciplinary approach and patient education are invaluable to achieve these good results.
author Vergara A,María Teresa
Rey G,Paula
author_facet Vergara A,María Teresa
Rey G,Paula
author_sort Vergara A,María Teresa
title Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
title_short Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
title_full Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
title_fullStr Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
title_full_unstemmed Enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
title_sort enfermedad inflamatoria intestinal y embarazo: experiencia de 16 años
publisher Sociedad Médica de Santiago
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100005
work_keys_str_mv AT vergaraamariateresa enfermedadinflamatoriaintestinalyembarazoexperienciade16anos
AT reygpaula enfermedadinflamatoriaintestinalyembarazoexperienciade16anos
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