Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional

Background: Metabolic control of diabetic pregnant women is assessed using glycated hemoglobin (HbAlc) levels and fasting blood sugar. Another glycated protein, namely fructosamine, can be an indicator of average glucose levels during the last three weeks. Aim: To evaluate plasma fructosamine as an...

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Autores principales:	Delgado M,Raúl, Novik A,Victoria, Cardemil M,Felipe, Santander A,Diego
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Fetal macrosomia Fructosamine Gestational diabetes
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100008
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spelling	oai:scielo:S0034-988720110011000082012-02-08Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacionalDelgado M,RaúlNovik A,VictoriaCardemil M,FelipeSantander A,Diego Fetal macrosomia Fructosamine Gestational diabetes Background: Metabolic control of diabetic pregnant women is assessed using glycated hemoglobin (HbAlc) levels and fasting blood sugar. Another glycated protein, namely fructosamine, can be an indicator of average glucose levels during the last three weeks. Aim: To evaluate plasma fructosamine as an indicator of glycemic control in women with gestational diabetes. Patients and Methods: Prospective cohort study of 41 pregnant women aged 30 to 37 years, with gestational and pre-gestational diabetes. Blood glucose, HbAlc, fructosamine were measured. Newborn weight, and other prenatal and postnatal variables, were used to evaluate the correlation between metabolic control and the presence or absence of macrosomia. Results: The correlation observed between fructosamine and fasting blood glucose (r = 0.627, p < 0.001) was superior to that of HbA1c and blood glucose (r = 0.516, p < 0.001). No association was observed between macrosomia and levels of fructosamine, nor between the other studied variables. Conclusions: Fructosamine levels were not associated with macrosomia, but it could be better for the evaluation of glycemic control in patients with gestational diabetes since it allows short-term monitoring.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.11 20112011-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100008es10.4067/S0034-98872011001100008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Fetal macrosomia Fructosamine Gestational diabetes
spellingShingle	Fetal macrosomia Fructosamine Gestational diabetes Delgado M,Raúl Novik A,Victoria Cardemil M,Felipe Santander A,Diego Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
description	Background: Metabolic control of diabetic pregnant women is assessed using glycated hemoglobin (HbAlc) levels and fasting blood sugar. Another glycated protein, namely fructosamine, can be an indicator of average glucose levels during the last three weeks. Aim: To evaluate plasma fructosamine as an indicator of glycemic control in women with gestational diabetes. Patients and Methods: Prospective cohort study of 41 pregnant women aged 30 to 37 years, with gestational and pre-gestational diabetes. Blood glucose, HbAlc, fructosamine were measured. Newborn weight, and other prenatal and postnatal variables, were used to evaluate the correlation between metabolic control and the presence or absence of macrosomia. Results: The correlation observed between fructosamine and fasting blood glucose (r = 0.627, p < 0.001) was superior to that of HbA1c and blood glucose (r = 0.516, p < 0.001). No association was observed between macrosomia and levels of fructosamine, nor between the other studied variables. Conclusions: Fructosamine levels were not associated with macrosomia, but it could be better for the evaluation of glycemic control in patients with gestational diabetes since it allows short-term monitoring.
author	Delgado M,Raúl Novik A,Victoria Cardemil M,Felipe Santander A,Diego
author_facet	Delgado M,Raúl Novik A,Victoria Cardemil M,Felipe Santander A,Diego
author_sort	Delgado M,Raúl
title	Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
title_short	Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
title_full	Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
title_fullStr	Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
title_full_unstemmed	Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
title_sort	utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100008
work_keys_str_mv	AT delgadomraul utilidaddelamediciondefructosaminacomoindicadordecontrolenpacientescondiabetesgestacionalypregestacional AT novikavictoria utilidaddelamediciondefructosaminacomoindicadordecontrolenpacientescondiabetesgestacionalypregestacional AT cardemilmfelipe utilidaddelamediciondefructosaminacomoindicadordecontrolenpacientescondiabetesgestacionalypregestacional AT santanderadiego utilidaddelamediciondefructosaminacomoindicadordecontrolenpacientescondiabetesgestacionalypregestacional
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Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional

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