Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile

Background: Intensity modulated radiotherapy (IMRT) is an important step forward in cancer treatment. Aim: To report the first experience in Chile with IMRT for prostate cancer and compare the results obtained with different doses. Patients and Methods: From January 1997 through June 2008, 156 patie...

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Autores principales:	Besa DC,Pelayo, Rosso A,Roberto, Bustos C,Marisa, Borghero,Yerko, Trucco B,Cristian, Mac-Namara H,Macarena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Prostatic neoplasms Radiotherapy Survival
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100009
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spelling	oai:scielo:S0034-988720110011000092012-02-08Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en ChileBesa DC,PelayoRosso A,RobertoBustos C,MarisaBorghero,YerkoTrucco B,CristianMac-Namara H,Macarena Prostatic neoplasms Radiotherapy Survival Background: Intensity modulated radiotherapy (IMRT) is an important step forward in cancer treatment. Aim: To report the first experience in Chile with IMRT for prostate cancer and compare the results obtained with different doses. Patients and Methods: From January 1997 through June 2008, 156 patients with a mean age of 70 years, were treated with radiotherapy and 121 with IMRT. Patients were staged according to American Commission on Cancer Staging. Their biochemical relapse risk was classified according to the MD Anderson classification. Patients were routinely checked during and after therapy to evaluate side effects and relapse. Results: Median follow up was 46 months (4-120). Overall five years survival was 85%. Biochemical relapse free five years survival for low, intermediate and high risk patients was 100, 82 and 70%, respectively. Biochemical relapse free survival for patients receiving radiotherapy doses over 76 Gy was 83%, compared to 30% for those receiving lower doses (p < 0.05). Urinary and gastrointestinal acute toxicity was low in 80% and 90% of patients respectively. Late toxicity developed in less than 3% of patients. Conclusions: IMRTforprostate cancer is readily available and safe in Chile. Biochemical disease free survival improved with higher doses with low toxicity rates.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.11 20112011-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100009es10.4067/S0034-98872011001100009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Prostatic neoplasms Radiotherapy Survival
spellingShingle	Prostatic neoplasms Radiotherapy Survival Besa DC,Pelayo Rosso A,Roberto Bustos C,Marisa Borghero,Yerko Trucco B,Cristian Mac-Namara H,Macarena Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile
description	Background: Intensity modulated radiotherapy (IMRT) is an important step forward in cancer treatment. Aim: To report the first experience in Chile with IMRT for prostate cancer and compare the results obtained with different doses. Patients and Methods: From January 1997 through June 2008, 156 patients with a mean age of 70 years, were treated with radiotherapy and 121 with IMRT. Patients were staged according to American Commission on Cancer Staging. Their biochemical relapse risk was classified according to the MD Anderson classification. Patients were routinely checked during and after therapy to evaluate side effects and relapse. Results: Median follow up was 46 months (4-120). Overall five years survival was 85%. Biochemical relapse free five years survival for low, intermediate and high risk patients was 100, 82 and 70%, respectively. Biochemical relapse free survival for patients receiving radiotherapy doses over 76 Gy was 83%, compared to 30% for those receiving lower doses (p < 0.05). Urinary and gastrointestinal acute toxicity was low in 80% and 90% of patients respectively. Late toxicity developed in less than 3% of patients. Conclusions: IMRTforprostate cancer is readily available and safe in Chile. Biochemical disease free survival improved with higher doses with low toxicity rates.
author	Besa DC,Pelayo Rosso A,Roberto Bustos C,Marisa Borghero,Yerko Trucco B,Cristian Mac-Namara H,Macarena
author_facet	Besa DC,Pelayo Rosso A,Roberto Bustos C,Marisa Borghero,Yerko Trucco B,Cristian Mac-Namara H,Macarena
author_sort	Besa DC,Pelayo
title	Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile
title_short	Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile
title_full	Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile
title_fullStr	Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile
title_full_unstemmed	Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile
title_sort	tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en chile
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001100009
work_keys_str_mv	AT besadcpelayo tratamientodelcancerdeprostataconradioterapiapormodulaciondeintensidadprimeraexperienciaenchile AT rossoaroberto tratamientodelcancerdeprostataconradioterapiapormodulaciondeintensidadprimeraexperienciaenchile AT bustoscmarisa tratamientodelcancerdeprostataconradioterapiapormodulaciondeintensidadprimeraexperienciaenchile AT borgheroyerko tratamientodelcancerdeprostataconradioterapiapormodulaciondeintensidadprimeraexperienciaenchile AT truccobcristian tratamientodelcancerdeprostataconradioterapiapormodulaciondeintensidadprimeraexperienciaenchile AT macnamarahmacarena tratamientodelcancerdeprostataconradioterapiapormodulaciondeintensidadprimeraexperienciaenchile
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Tratamiento del cáncer de próstata con radioterapia por modulación de intensidad, primera experiencia en Chile

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