Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos

Ergotism is a complication of the acute intoxication or chronic abuse of ergot derivatives. It may be manifested by a vasomotor syndrome with peripheral vascular disease frequently involving extremities. We report three patients infected with human immunodeficiency virus (HIV), in antiretroviral tre...

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Autores principales:	Acle,Santiago, Roca,Federico, Vacarezza,Mariela, Álvarez Rocha,Alfredo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Ergotamine Ergotism Ritonavir
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001200010
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spelling	oai:scielo:S0034-988720110012000102012-03-07Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casosAcle,SantiagoRoca,FedericoVacarezza,MarielaÁlvarez Rocha,Alfredo Ergotamine Ergotism Ritonavir Ergotism is a complication of the acute intoxication or chronic abuse of ergot derivatives. It may be manifested by a vasomotor syndrome with peripheral vascular disease frequently involving extremities. We report three patients infected with human immunodeficiency virus (HIV), in antiretroviral treatment (ART) that included a protease inhibitor as ritonavir, and had received self-medicated ergotamine. They developed symptoms of peripheral vascular disease and the physical examination showed no arterial pulses in the affected vessels. Arterial Doppler confirmed signs of diffuse arterial spasm in all of them. An arteriography was performed to the second patient and it showed obliteration of the distal sector of the ulnar and radial arteries. Ergotism secondary to ergotamine-ritonavir association was diagnosed. Patients were treated discontinuing the administration of involved drugs, arterial vasodilators and prophylactic anticoagulation, with marked improvement of symptoms.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.12 20112011-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001200010es10.4067/S0034-98872011001200010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Ergotamine Ergotism Ritonavir
spellingShingle	Ergotamine Ergotism Ritonavir Acle,Santiago Roca,Federico Vacarezza,Mariela Álvarez Rocha,Alfredo Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos
description	Ergotism is a complication of the acute intoxication or chronic abuse of ergot derivatives. It may be manifested by a vasomotor syndrome with peripheral vascular disease frequently involving extremities. We report three patients infected with human immunodeficiency virus (HIV), in antiretroviral treatment (ART) that included a protease inhibitor as ritonavir, and had received self-medicated ergotamine. They developed symptoms of peripheral vascular disease and the physical examination showed no arterial pulses in the affected vessels. Arterial Doppler confirmed signs of diffuse arterial spasm in all of them. An arteriography was performed to the second patient and it showed obliteration of the distal sector of the ulnar and radial arteries. Ergotism secondary to ergotamine-ritonavir association was diagnosed. Patients were treated discontinuing the administration of involved drugs, arterial vasodilators and prophylactic anticoagulation, with marked improvement of symptoms.
author	Acle,Santiago Roca,Federico Vacarezza,Mariela Álvarez Rocha,Alfredo
author_facet	Acle,Santiago Roca,Federico Vacarezza,Mariela Álvarez Rocha,Alfredo
author_sort	Acle,Santiago
title	Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos
title_short	Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos
title_full	Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos
title_fullStr	Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos
title_full_unstemmed	Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos
title_sort	ergotismo secundario a la asociación ergotamina-ritonavir: a propósito de 3 casos
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011001200010
work_keys_str_mv	AT aclesantiago ergotismosecundarioalaasociacionergotaminaritonavirapropositode3casos AT rocafederico ergotismosecundarioalaasociacionergotaminaritonavirapropositode3casos AT vacarezzamariela ergotismosecundarioalaasociacionergotaminaritonavirapropositode3casos AT alvarezrochaalfredo ergotismosecundarioalaasociacionergotaminaritonavirapropositode3casos
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Ergotismo secundario a la asociación ergotamina-ritonavir: A propósito de 3 casos

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