Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico

Primary cutaneous aggressive epidermotropic cytotoxic CD8 positive T cell lymphoma, is an uncommon disease, with an aggressive clinical behavior. Differentiation with other types of cutaneous T-cell lymphoma (CTCL) that express a CD8+ cells, is based only on clinical grounds and in certain morpholog...

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Autores principales:	Intriago B,Marvila, Peña O,Camila, Gray H,Ana María, Cabrera C,María Elena, Martínez C,Virginia
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2012
Materias:	Antineoplastic protocols Epidermis Primary cutaneous CD8+ lymphoma
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000300014
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spelling	oai:scielo:S0034-988720120003000142012-05-31Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínicoIntriago B,MarvilaPeña O,CamilaGray H,Ana MaríaCabrera C,María ElenaMartínez C,Virginia Antineoplastic protocols Epidermis Primary cutaneous CD8+ lymphoma Primary cutaneous aggressive epidermotropic cytotoxic CD8 positive T cell lymphoma, is an uncommon disease, with an aggressive clinical behavior. Differentiation with other types of cutaneous T-cell lymphoma (CTCL) that express a CD8+ cells, is based only on clinical grounds and in certain morphological characteristics, such as a marked epidermotropism with squamous cell necrosis. We report a 50-year-old male presenting with painless cutaneous lesions appearing in trunk, limbs, scalp and face, suggestive of cutaneous lymphoma. He was admitted to the hospital in bad conditions, with confluent papules and tumors, some of them ulcerated and with foul smelling honey-colored crusts, involving the complete body surface. Cutaneous biopsy demonstrated a CD8 positive epidermotropic cytotoxic T cell lymphoma. He was treated with chemotherapy with an excellent initial response, but cutaneous lesions reappeared after four cycles. He did not respond to rescue chemotherapy and died seven months after diagnosis.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.3 20122012-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000300014es10.4067/S0034-98872012000300014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antineoplastic protocols Epidermis Primary cutaneous CD8+ lymphoma
spellingShingle	Antineoplastic protocols Epidermis Primary cutaneous CD8+ lymphoma Intriago B,Marvila Peña O,Camila Gray H,Ana María Cabrera C,María Elena Martínez C,Virginia Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
description	Primary cutaneous aggressive epidermotropic cytotoxic CD8 positive T cell lymphoma, is an uncommon disease, with an aggressive clinical behavior. Differentiation with other types of cutaneous T-cell lymphoma (CTCL) that express a CD8+ cells, is based only on clinical grounds and in certain morphological characteristics, such as a marked epidermotropism with squamous cell necrosis. We report a 50-year-old male presenting with painless cutaneous lesions appearing in trunk, limbs, scalp and face, suggestive of cutaneous lymphoma. He was admitted to the hospital in bad conditions, with confluent papules and tumors, some of them ulcerated and with foul smelling honey-colored crusts, involving the complete body surface. Cutaneous biopsy demonstrated a CD8 positive epidermotropic cytotoxic T cell lymphoma. He was treated with chemotherapy with an excellent initial response, but cutaneous lesions reappeared after four cycles. He did not respond to rescue chemotherapy and died seven months after diagnosis.
author	Intriago B,Marvila Peña O,Camila Gray H,Ana María Cabrera C,María Elena Martínez C,Virginia
author_facet	Intriago B,Marvila Peña O,Camila Gray H,Ana María Cabrera C,María Elena Martínez C,Virginia
author_sort	Intriago B,Marvila
title	Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
title_short	Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
title_full	Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
title_fullStr	Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
title_full_unstemmed	Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico
title_sort	linfoma primario cutáneo agresivo epidermotrópico de células t citotóxicas cd8 positivo: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000300014
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Linfoma primario cutáneo agresivo epidermotrópico de células T citotóxicas CD8 positivo: Caso clínico

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