Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura

Background: Arterial gasometry is considered the gold standard for establishing a diagnosis of respiratory failure of any etiology. However, there are some circumstances in which it loses specificity, making necessary to consider other tests such as pulse oximetry to adequately determine hypoxemia....

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Autores principales: Florenzano V,Pablo, Letelier S,Luz María, Durán S. C,Josefina, Sanhueza C,Cristóbal, Toro C,Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2012
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000400012
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spelling oai:scielo:S0034-988720120004000122013-11-06Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literaturaFlorenzano V,PabloLetelier S,Luz MaríaDurán S. C,JosefinaSanhueza C,CristóbalToro C,Luis Anoxia Leukemia myeloid Leukocytosis Background: Arterial gasometry is considered the gold standard for establishing a diagnosis of respiratory failure of any etiology. However, there are some circumstances in which it loses specificity, making necessary to consider other tests such as pulse oximetry to adequately determine hypoxemia. We report a 67 years old patient with sudden hypoacusia, right hemiparesis and polypnea. His laboratory exams on admission, showed extreme hypoxemia in several readings, without correlation to the patient's clinical condition nor the pulse oximetry, and a leukocytosis of 800.000 cells x ml, with many immature cells. Chronic myeloid leukemia was diagnosed and treatment with hydroxyurea was initiated, achieving normalization in the arterial gases in accordance with the fall of the white cell count. Interpretation of laboratory findings according to the general clinical context of the patient allowed to suspect a spurious hypoxemia, saving the patient from unnecessary and risky interventions.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.4 20122012-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000400012es10.4067/S0034-98872012000400012
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Anoxia
Leukemia
myeloid
Leukocytosis
spellingShingle Anoxia
Leukemia
myeloid
Leukocytosis
Florenzano V,Pablo
Letelier S,Luz María
Durán S. C,Josefina
Sanhueza C,Cristóbal
Toro C,Luis
Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura
description Background: Arterial gasometry is considered the gold standard for establishing a diagnosis of respiratory failure of any etiology. However, there are some circumstances in which it loses specificity, making necessary to consider other tests such as pulse oximetry to adequately determine hypoxemia. We report a 67 years old patient with sudden hypoacusia, right hemiparesis and polypnea. His laboratory exams on admission, showed extreme hypoxemia in several readings, without correlation to the patient's clinical condition nor the pulse oximetry, and a leukocytosis of 800.000 cells x ml, with many immature cells. Chronic myeloid leukemia was diagnosed and treatment with hydroxyurea was initiated, achieving normalization in the arterial gases in accordance with the fall of the white cell count. Interpretation of laboratory findings according to the general clinical context of the patient allowed to suspect a spurious hypoxemia, saving the patient from unnecessary and risky interventions.
author Florenzano V,Pablo
Letelier S,Luz María
Durán S. C,Josefina
Sanhueza C,Cristóbal
Toro C,Luis
author_facet Florenzano V,Pablo
Letelier S,Luz María
Durán S. C,Josefina
Sanhueza C,Cristóbal
Toro C,Luis
author_sort Florenzano V,Pablo
title Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura
title_short Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura
title_full Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura
title_fullStr Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura
title_full_unstemmed Hipoxemia espuria por hiperleucocitosis: Reporte de un caso y revisión de la literatura
title_sort hipoxemia espuria por hiperleucocitosis: reporte de un caso y revisión de la literatura
publisher Sociedad Médica de Santiago
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000400012
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AT duranscjosefina hipoxemiaespuriaporhiperleucocitosisreportedeuncasoyrevisiondelaliteratura
AT sanhuezaccristobal hipoxemiaespuriaporhiperleucocitosisreportedeuncasoyrevisiondelaliteratura
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