Daño vascular asociado a uso de cocaína: Caso clínico

Background: Cocaine abuse is associated with an increased risk of cardiac and cerebrovascular events, such as myocardial infarction, sudden cardiac death, and ischemic stroke. The underlying mechanisms leading to these complications are not fully understood although intravascular thrombus formation...

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Autores principales: Massardo,Teresa, Pino,Ángela, Berrocal,Isabel, Castro,Gabriel, Prat,Hernán, Pereira,Jaime
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2012
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000400013
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spelling oai:scielo:S0034-988720120004000132013-11-06Daño vascular asociado a uso de cocaína: Caso clínicoMassardo,TeresaPino,ÁngelaBerrocal,IsabelCastro,GabrielPrat,HernánPereira,Jaime Cocaine Endothelium vascular Myocardial infarction Background: Cocaine abuse is associated with an increased risk of cardiac and cerebrovascular events, such as myocardial infarction, sudden cardiac death, and ischemic stroke. The underlying mechanisms leading to these complications are not fully understood although intravascular thrombus formation and accelerated atherosclerosis are prominent findings. We report a 39-year-old male addicted to cocaine, who presented with three consecutive ischemic events characterized by an acute myocardial infarction and two ischemic strokes complicated by cardiac failure and severe neurological sequelae. The pathophysiology of cocaine-induce vascular damage and the management of the ischemic complications are discussed.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.4 20122012-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000400013es10.4067/S0034-98872012000400013
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cocaine
Endothelium
vascular
Myocardial infarction
spellingShingle Cocaine
Endothelium
vascular
Myocardial infarction
Massardo,Teresa
Pino,Ángela
Berrocal,Isabel
Castro,Gabriel
Prat,Hernán
Pereira,Jaime
Daño vascular asociado a uso de cocaína: Caso clínico
description Background: Cocaine abuse is associated with an increased risk of cardiac and cerebrovascular events, such as myocardial infarction, sudden cardiac death, and ischemic stroke. The underlying mechanisms leading to these complications are not fully understood although intravascular thrombus formation and accelerated atherosclerosis are prominent findings. We report a 39-year-old male addicted to cocaine, who presented with three consecutive ischemic events characterized by an acute myocardial infarction and two ischemic strokes complicated by cardiac failure and severe neurological sequelae. The pathophysiology of cocaine-induce vascular damage and the management of the ischemic complications are discussed.
author Massardo,Teresa
Pino,Ángela
Berrocal,Isabel
Castro,Gabriel
Prat,Hernán
Pereira,Jaime
author_facet Massardo,Teresa
Pino,Ángela
Berrocal,Isabel
Castro,Gabriel
Prat,Hernán
Pereira,Jaime
author_sort Massardo,Teresa
title Daño vascular asociado a uso de cocaína: Caso clínico
title_short Daño vascular asociado a uso de cocaína: Caso clínico
title_full Daño vascular asociado a uso de cocaína: Caso clínico
title_fullStr Daño vascular asociado a uso de cocaína: Caso clínico
title_full_unstemmed Daño vascular asociado a uso de cocaína: Caso clínico
title_sort daño vascular asociado a uso de cocaína: caso clínico
publisher Sociedad Médica de Santiago
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000400013
work_keys_str_mv AT massardoteresa danovascularasociadoausodecocainacasoclinico
AT pinoangela danovascularasociadoausodecocainacasoclinico
AT berrocalisabel danovascularasociadoausodecocainacasoclinico
AT castrogabriel danovascularasociadoausodecocainacasoclinico
AT prathernan danovascularasociadoausodecocainacasoclinico
AT pereirajaime danovascularasociadoausodecocainacasoclinico
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