Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile

Background:The incidence of bacteremia has increased over the last decade due to the aging of the population and the wide implementation of invasive nosocomial procedures and wide-spectrum antimicrobial treatments. Aim: To assess the epidemiology of hospital and ambulatory bacteremias in a public ho...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gambra,María, Flores,Jeferson, Ramírez,Kathleen, Palma,Sofía, Zitko,Pedro, Valenzuela,María Teresa, Beltrán,Carlos
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2012
Materias:	Bacteremia Epidemiology Risk factors Survival
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000700005
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872012000700005
record_format	dspace
spelling	oai:scielo:S0034-988720120007000052012-10-22Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de ChileGambra,MaríaFlores,JefersonRamírez,KathleenPalma,SofíaZitko,PedroValenzuela,María TeresaBeltrán,Carlos Bacteremia Epidemiology Risk factors Survival Background:The incidence of bacteremia has increased over the last decade due to the aging of the population and the wide implementation of invasive nosocomial procedures and wide-spectrum antimicrobial treatments. Aim: To assess the epidemiology of hospital and ambulatory bacteremias in a public hospital in Santiago. Material and Methods: A prospective longitudinal cohort study of laboratory-confirmed adult patients with bacteremia was undertaken at a public hospital in Santiago, between June 1, 2007 and April 30, 2008. Demographic, clinical, and laboratory data was collected into a standardized study-specific form. Results: In the study period, 253 cases of true bacteremia were identified, with an incidence of 11 per 1,000 patient discharges (63.6% nosocomial, 36.7% fatal). Only 2/3 of the cohort was alive at day 28 of hospitalization. Variables associated with mortality were age with a hazard ratio (HR) of 2.31; (95% confidence intervals (CI) 1.42- 3.77); female gender (HR, 1.70; 95% CI 1.06- 2.71); shock (HR, 3.24; 95%CI 2.01-5.22); and C reactive protein (HR, 2.10; 95% CI 1.17- 3.78). The variable associated with lower mortality was surgery (HR, 0.43; 95% CI 0.25-0.75). Selective empiric treatment did not improve survival. Conclusions: Besides age and gender, survival can be influenced by modifiable variables such as presence of shock and surgical intervention, which may provide an opportunity to improve outcomes.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.7 20122012-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000700005es10.4067/S0034-98872012000700005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Bacteremia Epidemiology Risk factors Survival
spellingShingle	Bacteremia Epidemiology Risk factors Survival Gambra,María Flores,Jeferson Ramírez,Kathleen Palma,Sofía Zitko,Pedro Valenzuela,María Teresa Beltrán,Carlos Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile
description	Background:The incidence of bacteremia has increased over the last decade due to the aging of the population and the wide implementation of invasive nosocomial procedures and wide-spectrum antimicrobial treatments. Aim: To assess the epidemiology of hospital and ambulatory bacteremias in a public hospital in Santiago. Material and Methods: A prospective longitudinal cohort study of laboratory-confirmed adult patients with bacteremia was undertaken at a public hospital in Santiago, between June 1, 2007 and April 30, 2008. Demographic, clinical, and laboratory data was collected into a standardized study-specific form. Results: In the study period, 253 cases of true bacteremia were identified, with an incidence of 11 per 1,000 patient discharges (63.6% nosocomial, 36.7% fatal). Only 2/3 of the cohort was alive at day 28 of hospitalization. Variables associated with mortality were age with a hazard ratio (HR) of 2.31; (95% confidence intervals (CI) 1.42- 3.77); female gender (HR, 1.70; 95% CI 1.06- 2.71); shock (HR, 3.24; 95%CI 2.01-5.22); and C reactive protein (HR, 2.10; 95% CI 1.17- 3.78). The variable associated with lower mortality was surgery (HR, 0.43; 95% CI 0.25-0.75). Selective empiric treatment did not improve survival. Conclusions: Besides age and gender, survival can be influenced by modifiable variables such as presence of shock and surgical intervention, which may provide an opportunity to improve outcomes.
author	Gambra,María Flores,Jeferson Ramírez,Kathleen Palma,Sofía Zitko,Pedro Valenzuela,María Teresa Beltrán,Carlos
author_facet	Gambra,María Flores,Jeferson Ramírez,Kathleen Palma,Sofía Zitko,Pedro Valenzuela,María Teresa Beltrán,Carlos
author_sort	Gambra,María
title	Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile
title_short	Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile
title_full	Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile
title_fullStr	Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile
title_full_unstemmed	Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile
title_sort	incidencia y mortalidad de bacteriemia en un hospital clínico docente en santiago de chile
publisher	Sociedad Médica de Santiago
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000700005
work_keys_str_mv	AT gambramaria incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile AT floresjeferson incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile AT ramirezkathleen incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile AT palmasofia incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile AT zitkopedro incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile AT valenzuelamariateresa incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile AT beltrancarlos incidenciaymortalidaddebacteriemiaenunhospitalclinicodocenteensantiagodechile
_version_	1718436636828631040

Incidencia y mortalidad de bacteriemia en un hospital clínico docente en Santiago de Chile

Ejemplares similares