Genotipo y fenotipo de la enzima tiopurina metiltransferasa en población chilena
Background: Thiopurines (azathioprine and 6-mercaptopurine) are highly effective medications but with potential adverse effects. Thiopurine methyltransferase (TMPT) is the key enzyme in their pharmacokinetics and is genetically regulated. A low activity of TPMT is associated with myelotoxicity. The...
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| Main Authors: | , , , , , , , , , |
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| Language: | Spanish / Castilian |
| Published: |
Sociedad Médica de Santiago
2012
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| Subjects: | |
| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000700009 |
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