Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile

Background: Identification of patients at risk for severe disease early in the course of acute pancreatitis (AP) is essential to optimize management and to improve outcomes. Aim: To assess BISAP score as a predictor of severity of AP. Patients and Methods: Retrospective review of AP patients between...

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Autores principales: Gompertz,Macarena, Fernández,Lara, Lara,Ivone, Miranda,Juan Pablo, Mancilla,Carla, Berger,Zoltán
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2012
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800002
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spelling oai:scielo:S0034-988720120008000022012-12-18Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de ChileGompertz,MacarenaFernández,LaraLara,IvoneMiranda,Juan PabloMancilla,CarlaBerger,Zoltán Multiple organ failure Pancreatitis Severity of illness index Background: Identification of patients at risk for severe disease early in the course of acute pancreatitis (AP) is essential to optimize management and to improve outcomes. Aim: To assess BISAP score as a predictor of severity of AP. Patients and Methods: Retrospective review of AP patients between January 2009 and December 2010. BISAP, APACHE II and Balthazar scores were calculated. Length of stay, local complications, organ failure and mortality were registered. Accuracy of the scoring system for predicting severity was measured by the area under the receiver operating curve (AUC). Results: The medical records of 128 patients, median age 46.5 years (55.5% men), were reviewed. Mean hospital stay was 15 days, 18 patients (14%) had local complications, 7 patients (5.4%) developed organ failure and 2 patients died (1.6%). The AUC for BISAP score to detect organ failure was 0.977 (95% IC 0.947-1.000). A BISAP score > 3 had a sensitivity, specificity, positive and negative predictive value of 71.4, 99.1, 83.3 and 98.3% respectively. An APACHE II score > 8 had a sensitivity and specificity of 71.5 and 86.8% respectively. The figures for a Balthazar score > 6 were 42.8 and 98.3% respectively. There was a significant correlation between BISAP score and length of hospital stay. Conclusions: BISAP score was a useful method for predicting the severity of PA, with the advantage of being simple and based on parameters obtained on the first day of hospitalization. Its sensitivity and specificity were superior to APACHE II and Balthazar score in this cohort.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.8 20122012-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800002es10.4067/S0034-98872012000800002
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Multiple organ failure
Pancreatitis
Severity of illness index
spellingShingle Multiple organ failure
Pancreatitis
Severity of illness index
Gompertz,Macarena
Fernández,Lara
Lara,Ivone
Miranda,Juan Pablo
Mancilla,Carla
Berger,Zoltán
Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile
description Background: Identification of patients at risk for severe disease early in the course of acute pancreatitis (AP) is essential to optimize management and to improve outcomes. Aim: To assess BISAP score as a predictor of severity of AP. Patients and Methods: Retrospective review of AP patients between January 2009 and December 2010. BISAP, APACHE II and Balthazar scores were calculated. Length of stay, local complications, organ failure and mortality were registered. Accuracy of the scoring system for predicting severity was measured by the area under the receiver operating curve (AUC). Results: The medical records of 128 patients, median age 46.5 years (55.5% men), were reviewed. Mean hospital stay was 15 days, 18 patients (14%) had local complications, 7 patients (5.4%) developed organ failure and 2 patients died (1.6%). The AUC for BISAP score to detect organ failure was 0.977 (95% IC 0.947-1.000). A BISAP score > 3 had a sensitivity, specificity, positive and negative predictive value of 71.4, 99.1, 83.3 and 98.3% respectively. An APACHE II score > 8 had a sensitivity and specificity of 71.5 and 86.8% respectively. The figures for a Balthazar score > 6 were 42.8 and 98.3% respectively. There was a significant correlation between BISAP score and length of hospital stay. Conclusions: BISAP score was a useful method for predicting the severity of PA, with the advantage of being simple and based on parameters obtained on the first day of hospitalization. Its sensitivity and specificity were superior to APACHE II and Balthazar score in this cohort.
author Gompertz,Macarena
Fernández,Lara
Lara,Ivone
Miranda,Juan Pablo
Mancilla,Carla
Berger,Zoltán
author_facet Gompertz,Macarena
Fernández,Lara
Lara,Ivone
Miranda,Juan Pablo
Mancilla,Carla
Berger,Zoltán
author_sort Gompertz,Macarena
title Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile
title_short Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile
title_full Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile
title_fullStr Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile
title_full_unstemmed Índice clínico de gravedad en pancreatitis aguda: BISAP ("Bedside Index for Severity in Acute Pancreatitis"): Dos años de experiencia en el Hospital Clínico Universidad de Chile
title_sort índice clínico de gravedad en pancreatitis aguda: bisap ("bedside index for severity in acute pancreatitis"): dos años de experiencia en el hospital clínico universidad de chile
publisher Sociedad Médica de Santiago
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800002
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