Resultados del trasplante renal en portadores de ríñones poliquísticos

Background: Patients with autosomal dominant polycystic kidney disease (ADPKD) have a better survival in chronic dialysis than patients with other etiologies of renal failure. It has been suggested that extra-renal manifestations of ADPKD may increase the odds of complications and mortality, if thes...

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Autores principales:	Vega,Jorge, Lira,Daniel, Medel,Simón, Betancour,Pablo, Goecke,Helmuth, Carrasco,Alejandra
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2012
Materias:	Kidney transplantation Morbidity Mortality Polycystic kidney autosomal dominant
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800004
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spelling	oai:scielo:S0034-988720120008000042012-12-18Resultados del trasplante renal en portadores de ríñones poliquísticosVega,JorgeLira,DanielMedel,SimónBetancour,PabloGoecke,HelmuthCarrasco,Alejandra Kidney transplantation Morbidity Mortality Polycystic kidney autosomal dominant Background: Patients with autosomal dominant polycystic kidney disease (ADPKD) have a better survival in chronic dialysis than patients with other etiologies of renal failure. It has been suggested that extra-renal manifestations of ADPKD may increase the odds of complications and mortality, if these patients are transplanted. Aim: To determine whether survival and complications in transplanted patients with ADPKD are different from kidney graft recipients with other etiologies of renal failure. Subjects and Methods: Four hundred six patients with kidney transplantation were followed in three hospitals between 1976 and 2011 and 19 were carriers of ADPKD. The latter were matched by type of donor, gender, age and date of kidney transplant, with 38 graft recipients with other etiologies of renal failure. Results: Graft and patient 1, 5, 10 and 15 years survival were similar in both groups. Hospitalizations due to viral infections and sepsis were more common in patients with ADPKD. There were no differences in the rate of acute rejection, delayed graft function, cancer, gastrointestinal disorders and hospitalizations due to cardiovascular diseases. The frequency of graft loss due to death with a functioning kidney was similar between both groups. Conclusions: Patient and graft survival in transplanted patients with ADPKD were similar to patients with other etiologies of renal failure. The rate and type of complications were similar between groups with the exception of hospitalizations due to sepsis and viral infections, which were more common in ADPKD patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.8 20122012-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800004es10.4067/S0034-98872012000800004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Kidney transplantation Morbidity Mortality Polycystic kidney autosomal dominant
spellingShingle	Kidney transplantation Morbidity Mortality Polycystic kidney autosomal dominant Vega,Jorge Lira,Daniel Medel,Simón Betancour,Pablo Goecke,Helmuth Carrasco,Alejandra Resultados del trasplante renal en portadores de ríñones poliquísticos
description	Background: Patients with autosomal dominant polycystic kidney disease (ADPKD) have a better survival in chronic dialysis than patients with other etiologies of renal failure. It has been suggested that extra-renal manifestations of ADPKD may increase the odds of complications and mortality, if these patients are transplanted. Aim: To determine whether survival and complications in transplanted patients with ADPKD are different from kidney graft recipients with other etiologies of renal failure. Subjects and Methods: Four hundred six patients with kidney transplantation were followed in three hospitals between 1976 and 2011 and 19 were carriers of ADPKD. The latter were matched by type of donor, gender, age and date of kidney transplant, with 38 graft recipients with other etiologies of renal failure. Results: Graft and patient 1, 5, 10 and 15 years survival were similar in both groups. Hospitalizations due to viral infections and sepsis were more common in patients with ADPKD. There were no differences in the rate of acute rejection, delayed graft function, cancer, gastrointestinal disorders and hospitalizations due to cardiovascular diseases. The frequency of graft loss due to death with a functioning kidney was similar between both groups. Conclusions: Patient and graft survival in transplanted patients with ADPKD were similar to patients with other etiologies of renal failure. The rate and type of complications were similar between groups with the exception of hospitalizations due to sepsis and viral infections, which were more common in ADPKD patients.
author	Vega,Jorge Lira,Daniel Medel,Simón Betancour,Pablo Goecke,Helmuth Carrasco,Alejandra
author_facet	Vega,Jorge Lira,Daniel Medel,Simón Betancour,Pablo Goecke,Helmuth Carrasco,Alejandra
author_sort	Vega,Jorge
title	Resultados del trasplante renal en portadores de ríñones poliquísticos
title_short	Resultados del trasplante renal en portadores de ríñones poliquísticos
title_full	Resultados del trasplante renal en portadores de ríñones poliquísticos
title_fullStr	Resultados del trasplante renal en portadores de ríñones poliquísticos
title_full_unstemmed	Resultados del trasplante renal en portadores de ríñones poliquísticos
title_sort	resultados del trasplante renal en portadores de ríñones poliquísticos
publisher	Sociedad Médica de Santiago
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800004
work_keys_str_mv	AT vegajorge resultadosdeltrasplanterenalenportadoresderinonespoliquisticos AT liradaniel resultadosdeltrasplanterenalenportadoresderinonespoliquisticos AT medelsimon resultadosdeltrasplanterenalenportadoresderinonespoliquisticos AT betancourpablo resultadosdeltrasplanterenalenportadoresderinonespoliquisticos AT goeckehelmuth resultadosdeltrasplanterenalenportadoresderinonespoliquisticos AT carrascoalejandra resultadosdeltrasplanterenalenportadoresderinonespoliquisticos
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Resultados del trasplante renal en portadores de ríñones poliquísticos

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