Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico

Background: We report a 67-year-old man presenting with abdominal pain of acute onset, pallor, jaundice and behavioral changes after ingestion of fava beans. In the initial evaluation he appeared acutely ill and had resting dyspnea, edema and jaundice. His initial laboratory assessment disclosed azo...

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Autores principales: Torres C,Demetrio, Chandía C,Mauricio
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2012
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800011
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spelling oai:scielo:S0034-988720120008000112012-12-18Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínicoTorres C,DemetrioChandía C,Mauricio Favism Glucose-6-phosphate Hemolysis Jaundice Background: We report a 67-year-old man presenting with abdominal pain of acute onset, pallor, jaundice and behavioral changes after ingestion of fava beans. In the initial evaluation he appeared acutely ill and had resting dyspnea, edema and jaundice. His initial laboratory assessment disclosed azotemia, elevated lactate dehydrogenase levels, a low hemoglobin concentration (4.9 /dL) and a high corrected reticulocyte count (4,7%) with negative direct and indirect Coombs' test. The patient was transferred to the ICU, where he received support therapy with hemodialysis, mechanical ventilation, vasoactive drugs and transfusions of packed red cells. The evolution after 1 month was favorable and he was discharged without anemia and with normal renal function. Three months after discharge, the glucose-6-phosphate-dehydrogenase screening study did not demonstrate detectable enzymatic activity.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.8 20122012-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800011es10.4067/S0034-98872012000800011
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Favism
Glucose-6-phosphate
Hemolysis
Jaundice
spellingShingle Favism
Glucose-6-phosphate
Hemolysis
Jaundice
Torres C,Demetrio
Chandía C,Mauricio
Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico
description Background: We report a 67-year-old man presenting with abdominal pain of acute onset, pallor, jaundice and behavioral changes after ingestion of fava beans. In the initial evaluation he appeared acutely ill and had resting dyspnea, edema and jaundice. His initial laboratory assessment disclosed azotemia, elevated lactate dehydrogenase levels, a low hemoglobin concentration (4.9 /dL) and a high corrected reticulocyte count (4,7%) with negative direct and indirect Coombs' test. The patient was transferred to the ICU, where he received support therapy with hemodialysis, mechanical ventilation, vasoactive drugs and transfusions of packed red cells. The evolution after 1 month was favorable and he was discharged without anemia and with normal renal function. Three months after discharge, the glucose-6-phosphate-dehydrogenase screening study did not demonstrate detectable enzymatic activity.
author Torres C,Demetrio
Chandía C,Mauricio
author_facet Torres C,Demetrio
Chandía C,Mauricio
author_sort Torres C,Demetrio
title Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico
title_short Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico
title_full Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico
title_fullStr Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico
title_full_unstemmed Insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: Caso clínico
title_sort insuficiencia renal aguda secundaria como manifestación inicial de favismo en un adulto mayor: caso clínico
publisher Sociedad Médica de Santiago
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000800011
work_keys_str_mv AT torrescdemetrio insuficienciarenalagudasecundariacomomanifestacioninicialdefavismoenunadultomayorcasoclinico
AT chandiacmauricio insuficienciarenalagudasecundariacomomanifestacioninicialdefavismoenunadultomayorcasoclinico
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