Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case

Background: Limbic encephalitis is a subacute syndrome characterized by memory impairment, confusion, seizures, hypothalamic dysfunction and psychiatric symptoms. It has been associated to tumors located outside of the central nervous system. In 2007, anti-N-methyl-D-aspartate receptors (NMDAr) anti...

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Autores principales:	Martínez B,David, Guerrero T,Rodrigo, Grandjean B,Marcela, Cartier R,Luis
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2012
Materias:	Limbic encephalitis Nervous system Paraneoplastic syndromes Receptors N-methyl-D-aspartate
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000900010
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spelling	oai:scielo:S0034-988720120009000102013-01-02Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one caseMartínez B,DavidGuerrero T,RodrigoGrandjean B,MarcelaCartier R,Luis Limbic encephalitis Nervous system Paraneoplastic syndromes Receptors N-methyl-D-aspartate Background: Limbic encephalitis is a subacute syndrome characterized by memory impairment, confusion, seizures, hypothalamic dysfunction and psychiatric symptoms. It has been associated to tumors located outside of the central nervous system. In 2007, anti-N-methyl-D-aspartate receptors (NMDAr) antibodies were found in serum and CSF of patients with this particular type of encephalitis. We report a 25-year-old female who, following upper respiratory tract symptoms, developed serious behavioral and consciousness impairment that progressed to coma. Cerebrospinal fluid (CSF) analysis showed a lymphocyte pleocytosis, the electroencephalogram was altered with a slow encephalopathic rhythm and a brain magnetic resonance imaging was normal. Infectious etiologies were ruled out. CSF and serum anti NMDA receptors antibodies were positive.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.9 20122012-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000900010es10.4067/S0034-98872012000900010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Limbic encephalitis Nervous system Paraneoplastic syndromes Receptors N-methyl-D-aspartate
spellingShingle	Limbic encephalitis Nervous system Paraneoplastic syndromes Receptors N-methyl-D-aspartate Martínez B,David Guerrero T,Rodrigo Grandjean B,Marcela Cartier R,Luis Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case
description	Background: Limbic encephalitis is a subacute syndrome characterized by memory impairment, confusion, seizures, hypothalamic dysfunction and psychiatric symptoms. It has been associated to tumors located outside of the central nervous system. In 2007, anti-N-methyl-D-aspartate receptors (NMDAr) antibodies were found in serum and CSF of patients with this particular type of encephalitis. We report a 25-year-old female who, following upper respiratory tract symptoms, developed serious behavioral and consciousness impairment that progressed to coma. Cerebrospinal fluid (CSF) analysis showed a lymphocyte pleocytosis, the electroencephalogram was altered with a slow encephalopathic rhythm and a brain magnetic resonance imaging was normal. Infectious etiologies were ruled out. CSF and serum anti NMDA receptors antibodies were positive.
author	Martínez B,David Guerrero T,Rodrigo Grandjean B,Marcela Cartier R,Luis
author_facet	Martínez B,David Guerrero T,Rodrigo Grandjean B,Marcela Cartier R,Luis
author_sort	Martínez B,David
title	Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case
title_short	Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case
title_full	Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case
title_fullStr	Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case
title_full_unstemmed	Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case
title_sort	encefalitis autoinmune reversible y anticuerpos anti-receptores de n-metil-d-aspartato: report of one case
publisher	Sociedad Médica de Santiago
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000900010
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Encefalitis autoinmune reversible y anticuerpos anti-receptores de N-metil-D-aspartato: Report of one case

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