Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama

Background: Several studies have analyzed the relation between obesity and the hormonal imbalances generated by overweight and a family history of breast cancer. All of these factors are potentially implicated in the early development of breast cancer. Aim: To verify the existence of a significant r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	González Jiménez,Emilio, García López,Pedro A, Schmidt-Río-Valle,Jacqueline, Valenza,Carmen
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2012
Materias:	Breast neoplasms Menarche Obesity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012001000004
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872012001000004
record_format	dspace
spelling	oai:scielo:S0034-988720120010000042013-03-18Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mamaGonzález Jiménez,EmilioGarcía López,Pedro ASchmidt-Río-Valle,JacquelineValenza,Carmen Breast neoplasms Menarche Obesity Background: Several studies have analyzed the relation between obesity and the hormonal imbalances generated by overweight and a family history of breast cancer. All of these factors are potentially implicated in the early development of breast cancer. Aim: To verify the existence of a significant relation between the nutritional status of breast cancer patients, their hormone serum levels (estrogens, prolactin, and progesterone), and the existence of a family history of breast cancer. Material and Methods: Retrospective data was collected from clinical records of524 women diagnosed with breast cancer in a Spanish hospital. Results: There was a positive association between estrogen, progesterone and prolactin serum levels and body mass index. The elevations in hormone levels occurred earlier in life among women with a family history of breast cancer. A two way ANOVA found a significant association between progesterone and prolactin levels with the age at diagnosis of breast cancer. Conclusions: Extreme serum levels of these hormones appear to be related to the early development of breast cancer, which in turn is influenced by the existence of a family history of cancer among those women with normal or average hormone levels.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.140 n.10 20122012-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012001000004es10.4067/S0034-98872012001000004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Breast neoplasms Menarche Obesity
spellingShingle	Breast neoplasms Menarche Obesity González Jiménez,Emilio García López,Pedro A Schmidt-Río-Valle,Jacqueline Valenza,Carmen Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
description	Background: Several studies have analyzed the relation between obesity and the hormonal imbalances generated by overweight and a family history of breast cancer. All of these factors are potentially implicated in the early development of breast cancer. Aim: To verify the existence of a significant relation between the nutritional status of breast cancer patients, their hormone serum levels (estrogens, prolactin, and progesterone), and the existence of a family history of breast cancer. Material and Methods: Retrospective data was collected from clinical records of524 women diagnosed with breast cancer in a Spanish hospital. Results: There was a positive association between estrogen, progesterone and prolactin serum levels and body mass index. The elevations in hormone levels occurred earlier in life among women with a family history of breast cancer. A two way ANOVA found a significant association between progesterone and prolactin levels with the age at diagnosis of breast cancer. Conclusions: Extreme serum levels of these hormones appear to be related to the early development of breast cancer, which in turn is influenced by the existence of a family history of cancer among those women with normal or average hormone levels.
author	González Jiménez,Emilio García López,Pedro A Schmidt-Río-Valle,Jacqueline Valenza,Carmen
author_facet	González Jiménez,Emilio García López,Pedro A Schmidt-Río-Valle,Jacqueline Valenza,Carmen
author_sort	González Jiménez,Emilio
title	Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
title_short	Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
title_full	Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
title_fullStr	Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
title_full_unstemmed	Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
title_sort	influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama
publisher	Sociedad Médica de Santiago
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012001000004
work_keys_str_mv	AT gonzalezjimenezemilio influenciadelestadonutricionalniveleshormonalessericosehistoriafamiliardecancereneldesarrollodelcancerdemama AT garcialopezpedroa influenciadelestadonutricionalniveleshormonalessericosehistoriafamiliardecancereneldesarrollodelcancerdemama AT schmidtriovallejacqueline influenciadelestadonutricionalniveleshormonalessericosehistoriafamiliardecancereneldesarrollodelcancerdemama AT valenzacarmen influenciadelestadonutricionalniveleshormonalessericosehistoriafamiliardecancereneldesarrollodelcancerdemama
_version_	1718436652502745088

Influencia del estado nutricional, niveles hormonales séricos e historia familiar de cáncer en el desarrollo del cáncer de mama

Ejemplares similares