Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo
Background: Pulmonary arterial hypertension is an important cause ofcomplica-tions amongpatients with connective tissue diseases. Aim: To describe the clinical and echocardiographic characteristics ofpatients with pulmonary hypertension associated with connective tissue diseases. Material and Method...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2013
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oai:scielo:S0034-988720130001000082013-05-23Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivoÑamendys-Silva,Silvio AntonioOcotlán González-Herrera,MaríaHernández-Oropeza,José LuisRivero-Sigarroa,EduardoDomínguez-Cherit,Guillermo Connective tissue diseases Echocardiography Pulmonary Background: Pulmonary arterial hypertension is an important cause ofcomplica-tions amongpatients with connective tissue diseases. Aim: To describe the clinical and echocardiographic characteristics ofpatients with pulmonary hypertension associated with connective tissue diseases. Material and Methods: Retrospective, observational and descriptive study. We analyzed 35 patients with pulmonary hypertension associated with connective tissue diseases. All patients were evaluated and diagnosed by at least one medical specialist in rheumatology. Pulmonary arterial hypertension was defined as a pulmonary artery systolic pressure ≥ 40 mmHg by echocardiography. The group was divided as not severe when pressures ranged from 40 to 64 mmHg and severe, when pressures were ≥ 65 mmHg. Results: The most common connective tissue disease associated with pulmonary arterial hypertension was diffuse scleroderma in 46% of cases. Eighty nine percent of patients were female. Time of evolution of the pulmonary hypertension was 18.8 ± 21.8 months. The distance walked in the six minute walk test was < 400 m both in patients with and without severe pulmonary hypertension. Fifty one percent ofpatients had pulmonary restriction. No differences in gas exchange parameters were observed between groups. Comparing echocardio-graphic findings in patients with and without severe hypertension, the former had a higher frequency ofright ventricular dilatation (85.7 and 52.3% respectively, p = 0.04), right ventricular hypertrophy (42.8 and 0% respectively, p = 0.02) and right ventricular hypokinesia (71.4 and 9.5% respectively p = < 0.01). Conclusions: Patients with severe pulmonary arterial hypertension associated to connective tissue diseases have more commonly dilated, hypertrophic and hypokinetic right ventricles.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.1 20132013-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000100008es10.4067/S0034-98872013000100008 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Connective tissue diseases Echocardiography Pulmonary |
| spellingShingle |
Connective tissue diseases Echocardiography Pulmonary Ñamendys-Silva,Silvio Antonio Ocotlán González-Herrera,María Hernández-Oropeza,José Luis Rivero-Sigarroa,Eduardo Domínguez-Cherit,Guillermo Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| description |
Background: Pulmonary arterial hypertension is an important cause ofcomplica-tions amongpatients with connective tissue diseases. Aim: To describe the clinical and echocardiographic characteristics ofpatients with pulmonary hypertension associated with connective tissue diseases. Material and Methods: Retrospective, observational and descriptive study. We analyzed 35 patients with pulmonary hypertension associated with connective tissue diseases. All patients were evaluated and diagnosed by at least one medical specialist in rheumatology. Pulmonary arterial hypertension was defined as a pulmonary artery systolic pressure ≥ 40 mmHg by echocardiography. The group was divided as not severe when pressures ranged from 40 to 64 mmHg and severe, when pressures were ≥ 65 mmHg. Results: The most common connective tissue disease associated with pulmonary arterial hypertension was diffuse scleroderma in 46% of cases. Eighty nine percent of patients were female. Time of evolution of the pulmonary hypertension was 18.8 ± 21.8 months. The distance walked in the six minute walk test was < 400 m both in patients with and without severe pulmonary hypertension. Fifty one percent ofpatients had pulmonary restriction. No differences in gas exchange parameters were observed between groups. Comparing echocardio-graphic findings in patients with and without severe hypertension, the former had a higher frequency ofright ventricular dilatation (85.7 and 52.3% respectively, p = 0.04), right ventricular hypertrophy (42.8 and 0% respectively, p = 0.02) and right ventricular hypokinesia (71.4 and 9.5% respectively p = < 0.01). Conclusions: Patients with severe pulmonary arterial hypertension associated to connective tissue diseases have more commonly dilated, hypertrophic and hypokinetic right ventricles. |
| author |
Ñamendys-Silva,Silvio Antonio Ocotlán González-Herrera,María Hernández-Oropeza,José Luis Rivero-Sigarroa,Eduardo Domínguez-Cherit,Guillermo |
| author_facet |
Ñamendys-Silva,Silvio Antonio Ocotlán González-Herrera,María Hernández-Oropeza,José Luis Rivero-Sigarroa,Eduardo Domínguez-Cherit,Guillermo |
| author_sort |
Ñamendys-Silva,Silvio Antonio |
| title |
Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| title_short |
Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| title_full |
Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| title_fullStr |
Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| title_full_unstemmed |
Hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| title_sort |
hipertensión arterial pulmonar por ecocardiografía en pacientes con enfermedades de tejido conectivo |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2013 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000100008 |
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