Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad

Background: Mortality increases in adults, especially in older adults, after recovery from an episode of community-acquired pneumonia (CAP). Aim: To analyze survival and predictors of death at one year follow up of a cohort of adult patients hospitalized with CAP. Material and Methods: Immunocompete...

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Autores principales:	Saldías P,Fernando, Román O,Fernando, Maturana O,Rolando, Díaz P,Orlando
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Hospitalization Outcome assessment health care Pneumonia Prognosis Survival
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200001
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spelling	oai:scielo:S0034-988720130002000012013-05-24Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidadSaldías P,FernandoRomán O,FernandoMaturana O,RolandoDíaz P,Orlando Hospitalization Outcome assessment health care Pneumonia Prognosis Survival Background: Mortality increases in adults, especially in older adults, after recovery from an episode of community-acquired pneumonia (CAP). Aim: To analyze survival and predictors of death at one year follow up of a cohort of adult patients hospitalized with CAP. Material and Methods: Immunocompetent patients admitted to a clinical hospital for an episode of CAP were included in the study and were assessed according to a standardized protocol. One year mortality after admission was assessed using death records of the National Identification Service. Clinical and laboratory variables measured at hospital admission associated with risk of death at one year follow up were subjected to univariate and multivariate analysis by a logistic regression model. Results: We evaluated 659 patients aged 68 ± 19 years, 52% were male, 77% had underlying conditions (especially cardiovascular, neurological and respiratory diseases). Mean hospital length of stay was 9 days, 7.1% died during hospital stay and 15.8% did so during the year of follow-up. A causal agent was identified in one third of cases. The main pathogens isolated were Streptococcus pneumoniae (12.9%), Haemophilus influenzae (4.1%), respiratory viruses (6.5%) and Gram-negative bacilli (6.5%). In multivariate analysis, the clinical variables associated with increased risk of dying during the year of follow-up were older age, chronic neurological disease, malignancies, lack of fever at admission and prolonged hospital length of stay. Conclusions: Age, specific co-morbidities such as chronic neurological disease and cancer, absence of fever at hospital admission and prolonged hospital length of stay were associated with increased risk of dying during the year after admission among adult patients hospitalized with community-acquired pneumonia.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.2 20132013-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200001es10.4067/S0034-98872013000200001
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hospitalization Outcome assessment health care Pneumonia Prognosis Survival
spellingShingle	Hospitalization Outcome assessment health care Pneumonia Prognosis Survival Saldías P,Fernando Román O,Fernando Maturana O,Rolando Díaz P,Orlando Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
description	Background: Mortality increases in adults, especially in older adults, after recovery from an episode of community-acquired pneumonia (CAP). Aim: To analyze survival and predictors of death at one year follow up of a cohort of adult patients hospitalized with CAP. Material and Methods: Immunocompetent patients admitted to a clinical hospital for an episode of CAP were included in the study and were assessed according to a standardized protocol. One year mortality after admission was assessed using death records of the National Identification Service. Clinical and laboratory variables measured at hospital admission associated with risk of death at one year follow up were subjected to univariate and multivariate analysis by a logistic regression model. Results: We evaluated 659 patients aged 68 ± 19 years, 52% were male, 77% had underlying conditions (especially cardiovascular, neurological and respiratory diseases). Mean hospital length of stay was 9 days, 7.1% died during hospital stay and 15.8% did so during the year of follow-up. A causal agent was identified in one third of cases. The main pathogens isolated were Streptococcus pneumoniae (12.9%), Haemophilus influenzae (4.1%), respiratory viruses (6.5%) and Gram-negative bacilli (6.5%). In multivariate analysis, the clinical variables associated with increased risk of dying during the year of follow-up were older age, chronic neurological disease, malignancies, lack of fever at admission and prolonged hospital length of stay. Conclusions: Age, specific co-morbidities such as chronic neurological disease and cancer, absence of fever at hospital admission and prolonged hospital length of stay were associated with increased risk of dying during the year after admission among adult patients hospitalized with community-acquired pneumonia.
author	Saldías P,Fernando Román O,Fernando Maturana O,Rolando Díaz P,Orlando
author_facet	Saldías P,Fernando Román O,Fernando Maturana O,Rolando Díaz P,Orlando
author_sort	Saldías P,Fernando
title	Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
title_short	Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
title_full	Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
title_fullStr	Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
title_full_unstemmed	Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
title_sort	predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200001
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Predictores clínicos de mortalidad en el seguimiento a mediano plazo en pacientes adultos inmunocompetentes hospitalizados por neumonía adquirida en la comunidad

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