Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina

Background: Although polypharmacy may bejustified in elderly patients with multiple diseases, it may be dangerous, especially when it includes potentially inappropriate medications (PIM). Aim: To identify inappropriate medication and factors associated with the most relevant prescriptions among olde...

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Autores principales:	Marzi M,Marta, Diruscio A,Valeriana, Núñez H,Mariano, Pires S,Miryam, Quaglia B,Nora
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Aged Errors Inappropriate prescribing Polypharmacy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200008
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spelling	oai:scielo:S0034-988720130002000082013-05-24Análisis de la prescripción de medicamentos en una comunidad geriátrica ArgentinaMarzi M,MartaDiruscio A,ValerianaNúñez H,MarianoPires S,MiryamQuaglia B,Nora Aged Errors Inappropriate prescribing Polypharmacy Background: Although polypharmacy may bejustified in elderly patients with multiple diseases, it may be dangerous, especially when it includes potentially inappropriate medications (PIM). Aim: To identify inappropriate medication and factors associated with the most relevant prescriptions among older people. Material and Methods: Cross-sectional observational analysis of drugs prescribed during the first trimester of 2010 to 179 older adults aged 77 ± 8 years (98 women), living in a geriatric reference hospital in Argentina. The use of potentially inappropriate medications (PIM) in elderly patients was analyzed using Beers Criteria updated to 2012. Results: The mean number of drugs prescribed per individual was 6.1 ± 2.7. The most commonly used drugs were anti-ulcer agents (58.1%), agents acting on the renin-angiotensin system (54.2%), antithrombotic medications (50.8%) and benzodiazepines (50.8 %). The use of antacids and anti-ulcer agents, psychotropic drugs and PIM was significantly higher among patients using six or more drugs daily, compared to the less medicated group (odds ratio (OR) = 6.8, 95% confidence intervals (CI) 3.5-13.2; OR=15.0, 95%CI 5.9-38.4; OR=5.0; 95%IC 2.6-9.8, respectively). Thirty one percent of participants using non-steroidal anti-inflammatory drugs, were not receiving medications for gastric protection. One to four drugs included in the Beers list were prescribed to 66% of participants. Conclusions: Despite the high prevalence of use of antacids and anti-ulcer agents, these drugs were not prescribed to a significant proportion of patients using non-steroidal anti-inflammatory drugs. Strategies to optimize pharmacotherapy in the elderly population are urgently required.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.2 20132013-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200008es10.4067/S0034-98872013000200008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Aged Errors Inappropriate prescribing Polypharmacy
spellingShingle	Aged Errors Inappropriate prescribing Polypharmacy Marzi M,Marta Diruscio A,Valeriana Núñez H,Mariano Pires S,Miryam Quaglia B,Nora Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina
description	Background: Although polypharmacy may bejustified in elderly patients with multiple diseases, it may be dangerous, especially when it includes potentially inappropriate medications (PIM). Aim: To identify inappropriate medication and factors associated with the most relevant prescriptions among older people. Material and Methods: Cross-sectional observational analysis of drugs prescribed during the first trimester of 2010 to 179 older adults aged 77 ± 8 years (98 women), living in a geriatric reference hospital in Argentina. The use of potentially inappropriate medications (PIM) in elderly patients was analyzed using Beers Criteria updated to 2012. Results: The mean number of drugs prescribed per individual was 6.1 ± 2.7. The most commonly used drugs were anti-ulcer agents (58.1%), agents acting on the renin-angiotensin system (54.2%), antithrombotic medications (50.8%) and benzodiazepines (50.8 %). The use of antacids and anti-ulcer agents, psychotropic drugs and PIM was significantly higher among patients using six or more drugs daily, compared to the less medicated group (odds ratio (OR) = 6.8, 95% confidence intervals (CI) 3.5-13.2; OR=15.0, 95%CI 5.9-38.4; OR=5.0; 95%IC 2.6-9.8, respectively). Thirty one percent of participants using non-steroidal anti-inflammatory drugs, were not receiving medications for gastric protection. One to four drugs included in the Beers list were prescribed to 66% of participants. Conclusions: Despite the high prevalence of use of antacids and anti-ulcer agents, these drugs were not prescribed to a significant proportion of patients using non-steroidal anti-inflammatory drugs. Strategies to optimize pharmacotherapy in the elderly population are urgently required.
author	Marzi M,Marta Diruscio A,Valeriana Núñez H,Mariano Pires S,Miryam Quaglia B,Nora
author_facet	Marzi M,Marta Diruscio A,Valeriana Núñez H,Mariano Pires S,Miryam Quaglia B,Nora
author_sort	Marzi M,Marta
title	Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina
title_short	Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina
title_full	Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina
title_fullStr	Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina
title_full_unstemmed	Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina
title_sort	análisis de la prescripción de medicamentos en una comunidad geriátrica argentina
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200008
work_keys_str_mv	AT marzimmarta analisisdelaprescripciondemedicamentosenunacomunidadgeriatricaargentina AT diruscioavaleriana analisisdelaprescripciondemedicamentosenunacomunidadgeriatricaargentina AT nunezhmariano analisisdelaprescripciondemedicamentosenunacomunidadgeriatricaargentina AT piressmiryam analisisdelaprescripciondemedicamentosenunacomunidadgeriatricaargentina AT quagliabnora analisisdelaprescripciondemedicamentosenunacomunidadgeriatricaargentina
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Análisis de la prescripción de medicamentos en una comunidad geriátrica Argentina

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