Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico

Background: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular...

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Autores principales:	Avilés-Salas,Alejandro, Cruz Torres-Lucatero,José, Fernandez-Soto,Ximena, Candelaria-Hernández,Myrna
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Hemangio-endothelioma, epithelioid Lymph nodes Vascular neoplasms
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200017
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spelling	oai:scielo:S0034-988720130002000172013-05-24Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínicoAvilés-Salas,AlejandroCruz Torres-Lucatero,JoséFernandez-Soto,XimenaCandelaria-Hernández,Myrna Hemangio-endothelioma, epithelioid Lymph nodes Vascular neoplasms Background: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid hemangio-endothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70-year-old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracyto-plasmic vacuoles containing red blood cells. lmmunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.2 20132013-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200017es10.4067/S0034-98872013000200017
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hemangio-endothelioma, epithelioid Lymph nodes Vascular neoplasms
spellingShingle	Hemangio-endothelioma, epithelioid Lymph nodes Vascular neoplasms Avilés-Salas,Alejandro Cruz Torres-Lucatero,José Fernandez-Soto,Ximena Candelaria-Hernández,Myrna Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico
description	Background: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid hemangio-endothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70-year-old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracyto-plasmic vacuoles containing red blood cells. lmmunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.
author	Avilés-Salas,Alejandro Cruz Torres-Lucatero,José Fernandez-Soto,Ximena Candelaria-Hernández,Myrna
author_facet	Avilés-Salas,Alejandro Cruz Torres-Lucatero,José Fernandez-Soto,Ximena Candelaria-Hernández,Myrna
author_sort	Avilés-Salas,Alejandro
title	Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico
title_short	Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico
title_full	Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico
title_fullStr	Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico
title_full_unstemmed	Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico
title_sort	hemangioendotelioma epitelioide y fusiforme de ganglio linfático: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000200017
work_keys_str_mv	AT avilessalasalejandro hemangioendoteliomaepitelioideyfusiformedegangliolinfaticocasoclinico AT cruztorreslucaterojose hemangioendoteliomaepitelioideyfusiformedegangliolinfaticocasoclinico AT fernandezsotoximena hemangioendoteliomaepitelioideyfusiformedegangliolinfaticocasoclinico AT candelariahernandezmyrna hemangioendoteliomaepitelioideyfusiformedegangliolinfaticocasoclinico
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Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico

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