Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico
Celiac disease may be associated with other autoimmune diseases and exceptionally with glomerulopathies and nephrotic syndrome. Associations have been reported with IgA nephropathy, membranoproliferative glomerulonephritis, membranous glomerulopathy and minimal change disease. We report a 63-year-ol...
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Sociedad Médica de Santiago
2013
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oai:scielo:S0034-988720130003000152013-11-15Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínicoVega,JorgeDíaz,RienziMéndez,Gonzalo RGoecke,Helmuth Acute kidney injury Nephrotic syndrome Shock septic Celiac disease may be associated with other autoimmune diseases and exceptionally with glomerulopathies and nephrotic syndrome. Associations have been reported with IgA nephropathy, membranoproliferative glomerulonephritis, membranous glomerulopathy and minimal change disease. We report a 63-year-old woman who simultaneously presented with massive nephrotic syndrome (proteinuria 46 g/day) and cachexia due to a malabsorption syndrome secondary to celiac disease. The course of her diseases was complicated with cardiomyopathy due to severe malnutrition, septic shock, acute kidney injury that required dialysis for seven weeks and severe hypertension. A renal biopsy showed a membranoproliferative pattern of injury secondary to a thrombotic microangiopathy and diffuse podocyte damage. Four years later, the patient was in good general health, the glomerular filtration rate was 30 ml/min/1.73m² and there was non-nephrotic proteinuria.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.3 20132013-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000300015es10.4067/S0034-98872013000300015 |
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Scielo Chile |
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Scielo Chile |
language |
Spanish / Castilian |
topic |
Acute kidney injury Nephrotic syndrome Shock septic |
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Acute kidney injury Nephrotic syndrome Shock septic Vega,Jorge Díaz,Rienzi Méndez,Gonzalo R Goecke,Helmuth Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico |
description |
Celiac disease may be associated with other autoimmune diseases and exceptionally with glomerulopathies and nephrotic syndrome. Associations have been reported with IgA nephropathy, membranoproliferative glomerulonephritis, membranous glomerulopathy and minimal change disease. We report a 63-year-old woman who simultaneously presented with massive nephrotic syndrome (proteinuria 46 g/day) and cachexia due to a malabsorption syndrome secondary to celiac disease. The course of her diseases was complicated with cardiomyopathy due to severe malnutrition, septic shock, acute kidney injury that required dialysis for seven weeks and severe hypertension. A renal biopsy showed a membranoproliferative pattern of injury secondary to a thrombotic microangiopathy and diffuse podocyte damage. Four years later, the patient was in good general health, the glomerular filtration rate was 30 ml/min/1.73m² and there was non-nephrotic proteinuria. |
author |
Vega,Jorge Díaz,Rienzi Méndez,Gonzalo R Goecke,Helmuth |
author_facet |
Vega,Jorge Díaz,Rienzi Méndez,Gonzalo R Goecke,Helmuth |
author_sort |
Vega,Jorge |
title |
Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico |
title_short |
Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico |
title_full |
Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico |
title_fullStr |
Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico |
title_full_unstemmed |
Síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: Caso clínico |
title_sort |
síndrome nefrótico e injuria renal aguda con microangiopatía trombótica en mujer con enfermedad celíaca: caso clínico |
publisher |
Sociedad Médica de Santiago |
publishDate |
2013 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000300015 |
work_keys_str_mv |
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