Prevalence of congenital toxoplasmosis among a series of Turkish women

Background: Toxoplasma gondii infection during pregnancy causes congenital malformations. Pregnant women should be screened for this infection since it is preventable and treatable. Aim: To study the sero prevalence of Toxoplasma gondii infection among pregnant women living in lzmir, Turkey. Materia...

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Autores principales:	Uysal,Ahmet, Cüce,Mete, Tañer,Cüneyt E, Uysal,Fatma, Atalay,Sabri, Göl,Basak, Köse,Șükran
Lenguaje:	English
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Pregnancy Toxoplasmosis, congenital Toxoplasma gondii
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400008
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spelling	oai:scielo:S0034-988720130004000082013-09-11Prevalence of congenital toxoplasmosis among a series of Turkish womenUysal,AhmetCüce,MeteTañer,Cüneyt EUysal,FatmaAtalay,SabriGöl,BasakKöse,Șükran Pregnancy Toxoplasmosis, congenital Toxoplasma gondii Background: Toxoplasma gondii infection during pregnancy causes congenital malformations. Pregnant women should be screened for this infection since it is preventable and treatable. Aim: To study the sero prevalence of Toxoplasma gondii infection among pregnant women living in lzmir, Turkey. Material and Methods: A blood sample was obtained from 4651 women aged between 15 and 45years, during their first trimester of pregnancy. IgM and IgG antibodies against Toxoplasma gondii were measured using an ELISA assay. Among women with both IgG and IgM antibodies positive, an IgG avidity test was performed, using a VIDAS kit. Results: IgG antibodies were positive in 1871 (39.9%) participants. Of these, 48 (2.5%) also had positive IgM antibodies. In 41 ofthese 48 women, the IgG avidity test was performed and only one woman had a low avidity. This woman was treated with Spiramycin. Her offspring had an intrauterine growth retardation and oligohydramnios. A chorioretinitis was diagnosed in the offspring of other woman with both antibodies positive. Conclusions: In this series, the prevalence of congenital toxoplasmosis was low. However, women with positive antibodies against Toxoplasma Gondii should be further studied and followed during their pregnancy.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.4 20132013-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400008en10.4067/S0034-98872013000400008
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Pregnancy Toxoplasmosis, congenital Toxoplasma gondii
spellingShingle	Pregnancy Toxoplasmosis, congenital Toxoplasma gondii Uysal,Ahmet Cüce,Mete Tañer,Cüneyt E Uysal,Fatma Atalay,Sabri Göl,Basak Köse,Șükran Prevalence of congenital toxoplasmosis among a series of Turkish women
description	Background: Toxoplasma gondii infection during pregnancy causes congenital malformations. Pregnant women should be screened for this infection since it is preventable and treatable. Aim: To study the sero prevalence of Toxoplasma gondii infection among pregnant women living in lzmir, Turkey. Material and Methods: A blood sample was obtained from 4651 women aged between 15 and 45years, during their first trimester of pregnancy. IgM and IgG antibodies against Toxoplasma gondii were measured using an ELISA assay. Among women with both IgG and IgM antibodies positive, an IgG avidity test was performed, using a VIDAS kit. Results: IgG antibodies were positive in 1871 (39.9%) participants. Of these, 48 (2.5%) also had positive IgM antibodies. In 41 ofthese 48 women, the IgG avidity test was performed and only one woman had a low avidity. This woman was treated with Spiramycin. Her offspring had an intrauterine growth retardation and oligohydramnios. A chorioretinitis was diagnosed in the offspring of other woman with both antibodies positive. Conclusions: In this series, the prevalence of congenital toxoplasmosis was low. However, women with positive antibodies against Toxoplasma Gondii should be further studied and followed during their pregnancy.
author	Uysal,Ahmet Cüce,Mete Tañer,Cüneyt E Uysal,Fatma Atalay,Sabri Göl,Basak Köse,Șükran
author_facet	Uysal,Ahmet Cüce,Mete Tañer,Cüneyt E Uysal,Fatma Atalay,Sabri Göl,Basak Köse,Șükran
author_sort	Uysal,Ahmet
title	Prevalence of congenital toxoplasmosis among a series of Turkish women
title_short	Prevalence of congenital toxoplasmosis among a series of Turkish women
title_full	Prevalence of congenital toxoplasmosis among a series of Turkish women
title_fullStr	Prevalence of congenital toxoplasmosis among a series of Turkish women
title_full_unstemmed	Prevalence of congenital toxoplasmosis among a series of Turkish women
title_sort	prevalence of congenital toxoplasmosis among a series of turkish women
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400008
work_keys_str_mv	AT uysalahmet prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen AT cucemete prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen AT tanercuneyte prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen AT uysalfatma prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen AT atalaysabri prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen AT golbasak prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen AT kose536ukran prevalenceofcongenitaltoxoplasmosisamongaseriesofturkishwomen
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Prevalence of congenital toxoplasmosis among a series of Turkish women

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