Agregados amiloides: rol en desórdenes de conformación proteica

Misfolding and aggregation of proteins are the main features of a group of diseases termed Protein Misfolding Disorders (PMDs). PMDs include Alzheimer's disease and Transmissible Spongiform Encephalopathies, among many others. The deposition of protein aggregates is the main responsible for tis...

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Autores principales:	Duran-Aniotz,Claudia, Moreno-Gonzalez,Inés, Morales,Rodrigo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Alzheimers disease Amyloid Prion diseases Protein misfolding Protestasis deficiencies
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400011
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spelling	oai:scielo:S0034-988720130004000112013-09-11Agregados amiloides: rol en desórdenes de conformación proteicaDuran-Aniotz,ClaudiaMoreno-Gonzalez,InésMorales,Rodrigo Alzheimers disease Amyloid Prion diseases Protein misfolding Protestasis deficiencies Misfolding and aggregation of proteins are the main features of a group of diseases termed Protein Misfolding Disorders (PMDs). PMDs include Alzheimer's disease and Transmissible Spongiform Encephalopathies, among many others. The deposition of protein aggregates is the main responsible for tissue damage and the consequent clinical signs generated in such disorders. In this review, we will focus in the role of protein aggregates in these diseases and in the putative mechanisms by which they exert their toxicity.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.4 20132013-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400011es10.4067/S0034-98872013000400011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Alzheimers disease Amyloid Prion diseases Protein misfolding Protestasis deficiencies
spellingShingle	Alzheimers disease Amyloid Prion diseases Protein misfolding Protestasis deficiencies Duran-Aniotz,Claudia Moreno-Gonzalez,Inés Morales,Rodrigo Agregados amiloides: rol en desórdenes de conformación proteica
description	Misfolding and aggregation of proteins are the main features of a group of diseases termed Protein Misfolding Disorders (PMDs). PMDs include Alzheimer's disease and Transmissible Spongiform Encephalopathies, among many others. The deposition of protein aggregates is the main responsible for tissue damage and the consequent clinical signs generated in such disorders. In this review, we will focus in the role of protein aggregates in these diseases and in the putative mechanisms by which they exert their toxicity.
author	Duran-Aniotz,Claudia Moreno-Gonzalez,Inés Morales,Rodrigo
author_facet	Duran-Aniotz,Claudia Moreno-Gonzalez,Inés Morales,Rodrigo
author_sort	Duran-Aniotz,Claudia
title	Agregados amiloides: rol en desórdenes de conformación proteica
title_short	Agregados amiloides: rol en desórdenes de conformación proteica
title_full	Agregados amiloides: rol en desórdenes de conformación proteica
title_fullStr	Agregados amiloides: rol en desórdenes de conformación proteica
title_full_unstemmed	Agregados amiloides: rol en desórdenes de conformación proteica
title_sort	agregados amiloides: rol en desórdenes de conformación proteica
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400011
work_keys_str_mv	AT durananiotzclaudia agregadosamiloidesrolendesordenesdeconformacionproteica AT morenogonzalezines agregadosamiloidesrolendesordenesdeconformacionproteica AT moralesrodrigo agregadosamiloidesrolendesordenesdeconformacionproteica
_version_	1718436685091438592

Agregados amiloides: rol en desórdenes de conformación proteica

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