Pénfigo vulgar tipo cutáneo: Caso clínico

Pemphigus is an autoimmune bullous disease that involves skin and mucous membranes caused by autoantibodies against antigens on the surface of keratinocytes. We report a 30-year-old male presenting with a five months history of pruriginous alopecic and crusted lesions in the scalp, that extended pos...

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Autores principales:	Bello,Cristina, Mondaca-Cornejo,Luis, Navarrete-Dechent,Cristian, González,Sergio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Acantholysis Desmogleins Pemphigus
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400015
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spelling	oai:scielo:S0034-988720130004000152013-09-11Pénfigo vulgar tipo cutáneo: Caso clínicoBello,CristinaMondaca-Cornejo,LuisNavarrete-Dechent,CristianGonzález,Sergio Acantholysis Desmogleins Pemphigus Pemphigus is an autoimmune bullous disease that involves skin and mucous membranes caused by autoantibodies against antigens on the surface of keratinocytes. We report a 30-year-old male presenting with a five months history of pruriginous alopecic and crusted lesions in the scalp, that extended posteriorly to the trunk and limbs. Mucous membranes were not involved. A skin biopsy was performed, showing extensive loss of epidermis and acantholysis. Immuno fluorescence was positive for C3 and intercellular and epidermic IgG. With the presumptive diagnosis of pemphigus vulgaris (PV) without mucous involvement, the patient was treated with prednisone, observing an excellent clinical response. There are only few cases published in the literature of PV without mucous involvement. Some authors refer to this subtype of PV as "Cutaneous pemphigus vulgaris".info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.4 20132013-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400015es10.4067/S0034-98872013000400015
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Acantholysis Desmogleins Pemphigus
spellingShingle	Acantholysis Desmogleins Pemphigus Bello,Cristina Mondaca-Cornejo,Luis Navarrete-Dechent,Cristian González,Sergio Pénfigo vulgar tipo cutáneo: Caso clínico
description	Pemphigus is an autoimmune bullous disease that involves skin and mucous membranes caused by autoantibodies against antigens on the surface of keratinocytes. We report a 30-year-old male presenting with a five months history of pruriginous alopecic and crusted lesions in the scalp, that extended posteriorly to the trunk and limbs. Mucous membranes were not involved. A skin biopsy was performed, showing extensive loss of epidermis and acantholysis. Immuno fluorescence was positive for C3 and intercellular and epidermic IgG. With the presumptive diagnosis of pemphigus vulgaris (PV) without mucous involvement, the patient was treated with prednisone, observing an excellent clinical response. There are only few cases published in the literature of PV without mucous involvement. Some authors refer to this subtype of PV as "Cutaneous pemphigus vulgaris".
author	Bello,Cristina Mondaca-Cornejo,Luis Navarrete-Dechent,Cristian González,Sergio
author_facet	Bello,Cristina Mondaca-Cornejo,Luis Navarrete-Dechent,Cristian González,Sergio
author_sort	Bello,Cristina
title	Pénfigo vulgar tipo cutáneo: Caso clínico
title_short	Pénfigo vulgar tipo cutáneo: Caso clínico
title_full	Pénfigo vulgar tipo cutáneo: Caso clínico
title_fullStr	Pénfigo vulgar tipo cutáneo: Caso clínico
title_full_unstemmed	Pénfigo vulgar tipo cutáneo: Caso clínico
title_sort	pénfigo vulgar tipo cutáneo: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400015
work_keys_str_mv	AT bellocristina penfigovulgartipocutaneocasoclinico AT mondacacornejoluis penfigovulgartipocutaneocasoclinico AT navarretedechentcristian penfigovulgartipocutaneocasoclinico AT gonzalezsergio penfigovulgartipocutaneocasoclinico
_version_	1718436686066614272

Pénfigo vulgar tipo cutáneo: Caso clínico

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