Enfermedad de Von Economo: Caso clínico

Lethargic encephalitis (LE) is a Central Nervous System disorder following an upper respiratory tract infection, characterized by sleep disturbances, clinical symptoms corresponding to basal ganglia involvement and in some cases, neuropsychiatric sequelae. We report a 18-year-old mole with a history...

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Autores principales:	Vadalá,Sabrina F, Pellegrini,Débora, Silva,Emanuel D, Miñarro,Diego, Finn,Bárbara C, Bruetman,Julio E, Nápoli,Gabriel, Young,Pablo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Encephalitis Encephalitis lethargica type Parkinsonism Status epilepticus
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400016
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spelling	oai:scielo:S0034-988720130004000162013-09-11Enfermedad de Von Economo: Caso clínicoVadalá,Sabrina FPellegrini,DéboraSilva,Emanuel DMiñarro,DiegoFinn,Bárbara CBruetman,Julio ENápoli,GabrielYoung,Pablo Encephalitis Encephalitis lethargica type Parkinsonism Status epilepticus Lethargic encephalitis (LE) is a Central Nervous System disorder following an upper respiratory tract infection, characterized by sleep disturbances, clinical symptoms corresponding to basal ganglia involvement and in some cases, neuropsychiatric sequelae. We report a 18-year-old mole with a history of sinusitis treated with azithromycin, two weeks before, presenting with fever, headache, confusion and myoclonus. Urine analysis was positive for cannabis. Cerebro spinal fluid analysis showed mononuclear pleiocytosis (109xmm³) and an increase in protein concentration ofl.6 g/dl. Forty eight hours after admission, the patient required mechanical ventilation and subsequently a status epilepticus appeared. Ten days later, fever, rigidity and resting tremor appeared. A magnetic resonance imaging showed hyperintensities in FLALR sequence in the right insular cortex. The patient continued with extreme rigidity, catatonia and mutism. Considering the possibility ofa LE, methyl prednisolone 1 g/day was administered for five consecutive days followed by prednisone 40 mgl day, observing a dramatic improvement of rigidity and tremors.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.4 20132013-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400016es10.4067/S0034-98872013000400016
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Encephalitis Encephalitis lethargica type Parkinsonism Status epilepticus
spellingShingle	Encephalitis Encephalitis lethargica type Parkinsonism Status epilepticus Vadalá,Sabrina F Pellegrini,Débora Silva,Emanuel D Miñarro,Diego Finn,Bárbara C Bruetman,Julio E Nápoli,Gabriel Young,Pablo Enfermedad de Von Economo: Caso clínico
description	Lethargic encephalitis (LE) is a Central Nervous System disorder following an upper respiratory tract infection, characterized by sleep disturbances, clinical symptoms corresponding to basal ganglia involvement and in some cases, neuropsychiatric sequelae. We report a 18-year-old mole with a history of sinusitis treated with azithromycin, two weeks before, presenting with fever, headache, confusion and myoclonus. Urine analysis was positive for cannabis. Cerebro spinal fluid analysis showed mononuclear pleiocytosis (109xmm³) and an increase in protein concentration ofl.6 g/dl. Forty eight hours after admission, the patient required mechanical ventilation and subsequently a status epilepticus appeared. Ten days later, fever, rigidity and resting tremor appeared. A magnetic resonance imaging showed hyperintensities in FLALR sequence in the right insular cortex. The patient continued with extreme rigidity, catatonia and mutism. Considering the possibility ofa LE, methyl prednisolone 1 g/day was administered for five consecutive days followed by prednisone 40 mgl day, observing a dramatic improvement of rigidity and tremors.
author	Vadalá,Sabrina F Pellegrini,Débora Silva,Emanuel D Miñarro,Diego Finn,Bárbara C Bruetman,Julio E Nápoli,Gabriel Young,Pablo
author_facet	Vadalá,Sabrina F Pellegrini,Débora Silva,Emanuel D Miñarro,Diego Finn,Bárbara C Bruetman,Julio E Nápoli,Gabriel Young,Pablo
author_sort	Vadalá,Sabrina F
title	Enfermedad de Von Economo: Caso clínico
title_short	Enfermedad de Von Economo: Caso clínico
title_full	Enfermedad de Von Economo: Caso clínico
title_fullStr	Enfermedad de Von Economo: Caso clínico
title_full_unstemmed	Enfermedad de Von Economo: Caso clínico
title_sort	enfermedad de von economo: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000400016
work_keys_str_mv	AT vadalasabrinaf enfermedaddevoneconomocasoclinico AT pellegrinidebora enfermedaddevoneconomocasoclinico AT silvaemanueld enfermedaddevoneconomocasoclinico AT minarrodiego enfermedaddevoneconomocasoclinico AT finnbarbarac enfermedaddevoneconomocasoclinico AT bruetmanjulioe enfermedaddevoneconomocasoclinico AT napoligabriel enfermedaddevoneconomocasoclinico AT youngpablo enfermedaddevoneconomocasoclinico
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Enfermedad de Von Economo: Caso clínico

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