Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección

The description of Entamoeba dispar, and the recovery of Entamoeba moshkovskii from humans had a major impact in the epidemiology and clinical management of amebiasis. Infections range from asymptomatic colonization to hemorrhagic colitis and extra-intestinal diseases. Only a minority of amebiasis p...

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Autor principal: Chacín-Bonilla,Leonor
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2013
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000500009
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spelling oai:scielo:S0034-988720130005000092013-09-26Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infecciónChacín-Bonilla,Leonor Amebiasis Diagnosis Entamoeba histolytica Epidemiology Treatment The description of Entamoeba dispar, and the recovery of Entamoeba moshkovskii from humans had a major impact in the epidemiology and clinical management of amebiasis. Infections range from asymptomatic colonization to hemorrhagic colitis and extra-intestinal diseases. Only a minority of amebiasis patients progress to the development of disease. Recent studies suggest that susceptibility to infection, and its outcome is influenced by the host, parasite genotype, and environment. The identification of Entamoeba histolytica is based on the detection of specific antigens by ELISA and DNA in stool and other clinical samples. Several diagnostic tests have been developed, including polymerase chain reaction, the technique of choice, for the detection and differentiation of E. histolytica, E. dispar, and E. moshkovskii. Combination of serologic tests with detection of the parasite DNA by PCR or antigen by ELISA offers the best approach to diagnosis. However, these techniques are impractical for clinical laboratories of developing countries. Clinicians must follow the guidelines of the World Health Organization to avoid unnecessary treatments. This review describes and discusses recent advances in amebiasis with emphasis in the clinical aspects and management of infection.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.5 20132013-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000500009es10.4067/S0034-98872013000500009
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Amebiasis
Diagnosis
Entamoeba histolytica
Epidemiology
Treatment
spellingShingle Amebiasis
Diagnosis
Entamoeba histolytica
Epidemiology
Treatment
Chacín-Bonilla,Leonor
Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
description The description of Entamoeba dispar, and the recovery of Entamoeba moshkovskii from humans had a major impact in the epidemiology and clinical management of amebiasis. Infections range from asymptomatic colonization to hemorrhagic colitis and extra-intestinal diseases. Only a minority of amebiasis patients progress to the development of disease. Recent studies suggest that susceptibility to infection, and its outcome is influenced by the host, parasite genotype, and environment. The identification of Entamoeba histolytica is based on the detection of specific antigens by ELISA and DNA in stool and other clinical samples. Several diagnostic tests have been developed, including polymerase chain reaction, the technique of choice, for the detection and differentiation of E. histolytica, E. dispar, and E. moshkovskii. Combination of serologic tests with detection of the parasite DNA by PCR or antigen by ELISA offers the best approach to diagnosis. However, these techniques are impractical for clinical laboratories of developing countries. Clinicians must follow the guidelines of the World Health Organization to avoid unnecessary treatments. This review describes and discusses recent advances in amebiasis with emphasis in the clinical aspects and management of infection.
author Chacín-Bonilla,Leonor
author_facet Chacín-Bonilla,Leonor
author_sort Chacín-Bonilla,Leonor
title Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
title_short Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
title_full Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
title_fullStr Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
title_full_unstemmed Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
title_sort amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección
publisher Sociedad Médica de Santiago
publishDate 2013
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000500009
work_keys_str_mv AT chacinbonillaleonor amebiasisaspectosclinicosterapeuticosydediagnosticodelainfeccion
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