Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos
Background: Carotid intima-media thickness (IMT) is a surrogate marker of subclinical atherosderosis and is associated with cardiovascular risk factors (CVRF) Aim: To analyze the association of CVRF and metabolic factors (MF) with IMT, and if the clustering of these factors modify IMT. Material and...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2013
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oai:scielo:S0034-988720130006000022013-10-08Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicosVarleta,PaolaConcepción,RobertoVargas,PatricioCasanova,Héctor Atherosderosis Carotid intima-media thickness Metabolic syndrome Risk Factors Background: Carotid intima-media thickness (IMT) is a surrogate marker of subclinical atherosderosis and is associated with cardiovascular risk factors (CVRF) Aim: To analyze the association of CVRF and metabolic factors (MF) with IMT, and if the clustering of these factors modify IMT. Material and Methods: Cross sectional study in 187 participants aged 46±10years (53% male) without CV disease. Weight, height, waist circumference (WC), blood pressure, fasting plasma glucose and lipid profile were measured. Abdominal obesity (AOb) was defined by ATP III criteria. Mean carotid IMT was measured at the farwall of the common carotid artery. The cutoff point for an abnormally high IMT was set at the 75th IMT percentile of the sample. Results: The 75th IMT percentile of the sample was 0.67 mm. In a multivariate analysis four factors were significantly related with a high IMT: age (odds ratio (OR): 5.3, confidence intervals (CI): 2.2-12.9), dyslipidemia (OR: 6.4 CI: 2.3-17.9), systolic blood pressure (OR: 2.9, CI: 1.2-7.1) and AOb (OR: 2.9 (IC: 1.1-7.2). The presence of Oto 4 of these factors was associated with an IMT increment from 0.54 to 0.71 mm (p < 0,001). Conclusions: In this sample dyslipidemia, systolic blood pressure and abdominal obesity were the main predictors of a high IMT.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.6 20132013-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000600002es10.4067/S0034-98872013000600002 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Atherosderosis Carotid intima-media thickness Metabolic syndrome Risk Factors |
| spellingShingle |
Atherosderosis Carotid intima-media thickness Metabolic syndrome Risk Factors Varleta,Paola Concepción,Roberto Vargas,Patricio Casanova,Héctor Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| description |
Background: Carotid intima-media thickness (IMT) is a surrogate marker of subclinical atherosderosis and is associated with cardiovascular risk factors (CVRF) Aim: To analyze the association of CVRF and metabolic factors (MF) with IMT, and if the clustering of these factors modify IMT. Material and Methods: Cross sectional study in 187 participants aged 46±10years (53% male) without CV disease. Weight, height, waist circumference (WC), blood pressure, fasting plasma glucose and lipid profile were measured. Abdominal obesity (AOb) was defined by ATP III criteria. Mean carotid IMT was measured at the farwall of the common carotid artery. The cutoff point for an abnormally high IMT was set at the 75th IMT percentile of the sample. Results: The 75th IMT percentile of the sample was 0.67 mm. In a multivariate analysis four factors were significantly related with a high IMT: age (odds ratio (OR): 5.3, confidence intervals (CI): 2.2-12.9), dyslipidemia (OR: 6.4 CI: 2.3-17.9), systolic blood pressure (OR: 2.9, CI: 1.2-7.1) and AOb (OR: 2.9 (IC: 1.1-7.2). The presence of Oto 4 of these factors was associated with an IMT increment from 0.54 to 0.71 mm (p < 0,001). Conclusions: In this sample dyslipidemia, systolic blood pressure and abdominal obesity were the main predictors of a high IMT. |
| author |
Varleta,Paola Concepción,Roberto Vargas,Patricio Casanova,Héctor |
| author_facet |
Varleta,Paola Concepción,Roberto Vargas,Patricio Casanova,Héctor |
| author_sort |
Varleta,Paola |
| title |
Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| title_short |
Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| title_full |
Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| title_fullStr |
Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| title_full_unstemmed |
Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| title_sort |
grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2013 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000600002 |
| work_keys_str_mv |
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| _version_ |
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