Nuevas estrategias en el tratamiento del síndrome antifosfolípido

For years the mainstay of antiphospholipid syndrome treatment has been anticoagulation and antiplatelet therapy, but the autoimmune nature of the disease, and complications of these therapies, created the need to develop new therapeutic strategies. New therapeutic alternatives inhibit at different l...

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Autores principales: Ibáñez,Sebastián, Iruretagoyena,Mirentxu, Gutiérrez,Miguel A
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2013
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000800011
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spelling oai:scielo:S0034-988720130008000112014-01-27Nuevas estrategias en el tratamiento del síndrome antifosfolípidoIbáñez,SebastiánIruretagoyena,MirentxuGutiérrez,Miguel A Antiphospholipid syndrome Hydroxychloroquine, Hydroxymethylglutaryl-CoA Reductase Inhibitors Therapies, investigational For years the mainstay of antiphospholipid syndrome treatment has been anticoagulation and antiplatelet therapy, but the autoimmune nature of the disease, and complications of these therapies, created the need to develop new therapeutic strategies. New therapeutic alternatives inhibit at different levels, the cascade of events leading to the pro-thrombotic state characteristic of the antiphospholipid syndrome. We conducted a literature review of these new treatments, focusing on the pathophysiological bases that support them and their possible clinical applications.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.8 20132013-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000800011es10.4067/S0034-98872013000800011
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Antiphospholipid syndrome
Hydroxychloroquine, Hydroxymethylglutaryl-CoA Reductase Inhibitors
Therapies, investigational
spellingShingle Antiphospholipid syndrome
Hydroxychloroquine, Hydroxymethylglutaryl-CoA Reductase Inhibitors
Therapies, investigational
Ibáñez,Sebastián
Iruretagoyena,Mirentxu
Gutiérrez,Miguel A
Nuevas estrategias en el tratamiento del síndrome antifosfolípido
description For years the mainstay of antiphospholipid syndrome treatment has been anticoagulation and antiplatelet therapy, but the autoimmune nature of the disease, and complications of these therapies, created the need to develop new therapeutic strategies. New therapeutic alternatives inhibit at different levels, the cascade of events leading to the pro-thrombotic state characteristic of the antiphospholipid syndrome. We conducted a literature review of these new treatments, focusing on the pathophysiological bases that support them and their possible clinical applications.
author Ibáñez,Sebastián
Iruretagoyena,Mirentxu
Gutiérrez,Miguel A
author_facet Ibáñez,Sebastián
Iruretagoyena,Mirentxu
Gutiérrez,Miguel A
author_sort Ibáñez,Sebastián
title Nuevas estrategias en el tratamiento del síndrome antifosfolípido
title_short Nuevas estrategias en el tratamiento del síndrome antifosfolípido
title_full Nuevas estrategias en el tratamiento del síndrome antifosfolípido
title_fullStr Nuevas estrategias en el tratamiento del síndrome antifosfolípido
title_full_unstemmed Nuevas estrategias en el tratamiento del síndrome antifosfolípido
title_sort nuevas estrategias en el tratamiento del síndrome antifosfolípido
publisher Sociedad Médica de Santiago
publishDate 2013
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000800011
work_keys_str_mv AT ibanezsebastian nuevasestrategiaseneltratamientodelsindromeantifosfolipido
AT iruretagoyenamirentxu nuevasestrategiaseneltratamientodelsindromeantifosfolipido
AT gutierrezmiguela nuevasestrategiaseneltratamientodelsindromeantifosfolipido
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