Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa

Sepsis is a global health problem. Despite recent advances in understanding its pathophysiology and clinical trials testing potential new therapies, mortality remains unacceptably high. In fact, sepsis is the leading cause of death in non-coronary intensive care units around the world. However, duri...

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Autores principales:	Romero P,Carlos, Hernández P,Glenn
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2013
Materias:	Intensive care units Reperfusion Resuscitation Sepsis Shock, septic
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000900010
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spelling	oai:scielo:S0034-988720130009000102014-09-02Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severaRomero P,CarlosHernández P,Glenn Intensive care units Reperfusion Resuscitation Sepsis Shock, septic Sepsis is a global health problem. Despite recent advances in understanding its pathophysiology and clinical trials testing potential new therapies, mortality remains unacceptably high. In fact, sepsis is the leading cause of death in non-coronary intensive care units around the world. However, during the past decade, some studies have highlighted that early recognition of sepsis and an appropriate initial approach are fundamental determinants of prognosis. A systematic approach to the harmful triad of sepsis-related hypotension, tissue hypoperfusion and organ dysfunction, with low-cost, easy to implement, and effective interventions, can significantly improve the chances of survival. In this article, we will update the evidence supporting the initial resuscitation bundle for patients with severe sepsis, and discuss the physiological basis for perfusion monitoring during septic shock resuscitation.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.141 n.9 20132013-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000900010es10.4067/S0034-98872013000900010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Intensive care units Reperfusion Resuscitation Sepsis Shock, septic
spellingShingle	Intensive care units Reperfusion Resuscitation Sepsis Shock, septic Romero P,Carlos Hernández P,Glenn Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
description	Sepsis is a global health problem. Despite recent advances in understanding its pathophysiology and clinical trials testing potential new therapies, mortality remains unacceptably high. In fact, sepsis is the leading cause of death in non-coronary intensive care units around the world. However, during the past decade, some studies have highlighted that early recognition of sepsis and an appropriate initial approach are fundamental determinants of prognosis. A systematic approach to the harmful triad of sepsis-related hypotension, tissue hypoperfusion and organ dysfunction, with low-cost, easy to implement, and effective interventions, can significantly improve the chances of survival. In this article, we will update the evidence supporting the initial resuscitation bundle for patients with severe sepsis, and discuss the physiological basis for perfusion monitoring during septic shock resuscitation.
author	Romero P,Carlos Hernández P,Glenn
author_facet	Romero P,Carlos Hernández P,Glenn
author_sort	Romero P,Carlos
title	Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
title_short	Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
title_full	Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
title_fullStr	Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
title_full_unstemmed	Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
title_sort	actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa
publisher	Sociedad Médica de Santiago
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000900010
work_keys_str_mv	AT romeropcarlos actualizaciondelbundledereanimacioninicialymonitorizacionintegraldelaperfusiontisularenlasepsissevera AT hernandezpglenn actualizaciondelbundledereanimacioninicialymonitorizacionintegraldelaperfusiontisularenlasepsissevera
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Actualización del bundle de reanimación inicial y monitorización integral de la perfusión tisular en la sepsis severa

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