Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento

Non-resolving pneumonia is a common clinical problem that prolongs morbidity and increases hospitalization costs. We report an 82 year-old non-smoking female who was admitted with chronic diarrhea and later developed nosocomial pneumonia. Lung infiltrates did not resolve despite sequential antibioti...

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Autores principales:	Olivares A,Felipe, Fica C,Alberto, Charpentier V,Paulo, Hernández M,Antonio, Manríquez A,María Eugenia, Castro S,Marcelo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Adrenal cortex hormones Pneumonia Respiratory tract infections
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000200017
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spelling	oai:scielo:S0034-988720140002000172014-08-18Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamientoOlivares A,FelipeFica C,AlbertoCharpentier V,PauloHernández M,AntonioManríquez A,María EugeniaCastro S,Marcelo Adrenal cortex hormones Pneumonia Respiratory tract infections Non-resolving pneumonia is a common clinical problem that prolongs morbidity and increases hospitalization costs. We report an 82 year-old non-smoking female who was admitted with chronic diarrhea and later developed nosocomial pneumonia. Lung infiltrates did not resolve despite sequential antibiotic treatments. Infectious causes such as resistant nosocomial pathogens, respiratory viruses, tuberculosis, Legionellosis, cytomegalovirus or agents associated with HIV infection were discarded. Non-infectious causes such as thromboembolic lung disease, neoplasms and rheumatic disorders were also ruled out. An exudative pleural effusion was detected, but the study was unremarkable. Fiberoptic bronchoscopy and a transbronchial biopsy, revealed nonspecific findings. The patient persisted febrile, required non-invasive mechanical ventilation and displayed a migratory pattern of lung infiltrates that motivated a second biopsy, this time by open thoracotomy, showing a cryptogenic organizing pneumonia. The patient's conditions improved after treatment with adrenal steroids. In patients with non-resolving pneumonia, a dedicated and comprehensive study should be done using invasive procedures and considering both infectious and non-infectious causes. Cryptogenic organizing pneumonia is one of the alternatives that is potentially treatable, but often underdiagnosed.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.2 20142014-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000200017es10.4067/S0034-98872014000200017
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Adrenal cortex hormones Pneumonia Respiratory tract infections
spellingShingle	Adrenal cortex hormones Pneumonia Respiratory tract infections Olivares A,Felipe Fica C,Alberto Charpentier V,Paulo Hernández M,Antonio Manríquez A,María Eugenia Castro S,Marcelo Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
description	Non-resolving pneumonia is a common clinical problem that prolongs morbidity and increases hospitalization costs. We report an 82 year-old non-smoking female who was admitted with chronic diarrhea and later developed nosocomial pneumonia. Lung infiltrates did not resolve despite sequential antibiotic treatments. Infectious causes such as resistant nosocomial pathogens, respiratory viruses, tuberculosis, Legionellosis, cytomegalovirus or agents associated with HIV infection were discarded. Non-infectious causes such as thromboembolic lung disease, neoplasms and rheumatic disorders were also ruled out. An exudative pleural effusion was detected, but the study was unremarkable. Fiberoptic bronchoscopy and a transbronchial biopsy, revealed nonspecific findings. The patient persisted febrile, required non-invasive mechanical ventilation and displayed a migratory pattern of lung infiltrates that motivated a second biopsy, this time by open thoracotomy, showing a cryptogenic organizing pneumonia. The patient's conditions improved after treatment with adrenal steroids. In patients with non-resolving pneumonia, a dedicated and comprehensive study should be done using invasive procedures and considering both infectious and non-infectious causes. Cryptogenic organizing pneumonia is one of the alternatives that is potentially treatable, but often underdiagnosed.
author	Olivares A,Felipe Fica C,Alberto Charpentier V,Paulo Hernández M,Antonio Manríquez A,María Eugenia Castro S,Marcelo
author_facet	Olivares A,Felipe Fica C,Alberto Charpentier V,Paulo Hernández M,Antonio Manríquez A,María Eugenia Castro S,Marcelo
author_sort	Olivares A,Felipe
title	Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
title_short	Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
title_full	Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
title_fullStr	Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
title_full_unstemmed	Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
title_sort	neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000200017
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Neumonía criptogénica organizada como diagnóstico diferencial de neumonía que no responde a tratamiento

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