Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría

Background: Despite the low frequency of thyroid nodules (TN) in children, one of every four is malignant. Fine-needle aspiration cytology (FNAC) has a high accuracy detecting thyroid cancer. Aim: To evaluate the performance of FNAC in TN in Chilean children to detect thyroid cancer. Patients and Me...

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Autores principales:	Grob,Francisca, Carrillo,Diego, Martínez-Aguayo,Alejandro, Zoroquain,Pablo, Solar,Antonieta, Nicolaides,Irini, González,Hernán
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Cytology Child Thyroid neoplasms Thyroidectomy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000300007
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spelling	oai:scielo:S0034-988720140003000072014-09-02Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatríaGrob,FranciscaCarrillo,DiegoMartínez-Aguayo,AlejandroZoroquain,PabloSolar,AntonietaNicolaides,IriniGonzález,Hernán Cytology Child Thyroid neoplasms Thyroidectomy Background: Despite the low frequency of thyroid nodules (TN) in children, one of every four is malignant. Fine-needle aspiration cytology (FNAC) has a high accuracy detecting thyroid cancer. Aim: To evaluate the performance of FNAC in TN in Chilean children to detect thyroid cancer. Patients and Methods: The pathological reports of 77 thyroidectomies and 103 FNAC carried out in patients aged less than 18 years, between 2002 and 2013 were reviewed. In 36 patients aged 15 ± 2 years (77% women), both the reports of the thyroidectomy and FNAC were available. The cytological specimens were reclassified based on Bethesda 2010. The histology was classified as benign (nodular hyperplasia and follicular adenoma, n = 18), or malignant (papillary, follicular and medullar carcinoma, n = 18). The concordance of the cytology with the final biopsy report was calculated. Results: FNAC classified 13 specimens as definitively benign and 13 as definitively malignant. Among these, these concordances with the pathological study of the biopsy was 100%. Of six cytology tests considered "suspicious for follicular neoplasm" by FNAC, four were benign (67%), and two malignant (33%). Of four cytology tests considered "suggestive of carcinoma" by FNAC, one was benign (25%), and three malignant (75%). Conclusions: Among the studied children, there was a good concordance between FNAC and surgical biopsies. Therefore a FNAC should be carried out when malignancy is suspected in pediatric patients with a TN.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.3 20142014-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000300007es10.4067/S0034-98872014000300007
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cytology Child Thyroid neoplasms Thyroidectomy
spellingShingle	Cytology Child Thyroid neoplasms Thyroidectomy Grob,Francisca Carrillo,Diego Martínez-Aguayo,Alejandro Zoroquain,Pablo Solar,Antonieta Nicolaides,Irini González,Hernán Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
description	Background: Despite the low frequency of thyroid nodules (TN) in children, one of every four is malignant. Fine-needle aspiration cytology (FNAC) has a high accuracy detecting thyroid cancer. Aim: To evaluate the performance of FNAC in TN in Chilean children to detect thyroid cancer. Patients and Methods: The pathological reports of 77 thyroidectomies and 103 FNAC carried out in patients aged less than 18 years, between 2002 and 2013 were reviewed. In 36 patients aged 15 ± 2 years (77% women), both the reports of the thyroidectomy and FNAC were available. The cytological specimens were reclassified based on Bethesda 2010. The histology was classified as benign (nodular hyperplasia and follicular adenoma, n = 18), or malignant (papillary, follicular and medullar carcinoma, n = 18). The concordance of the cytology with the final biopsy report was calculated. Results: FNAC classified 13 specimens as definitively benign and 13 as definitively malignant. Among these, these concordances with the pathological study of the biopsy was 100%. Of six cytology tests considered "suspicious for follicular neoplasm" by FNAC, four were benign (67%), and two malignant (33%). Of four cytology tests considered "suggestive of carcinoma" by FNAC, one was benign (25%), and three malignant (75%). Conclusions: Among the studied children, there was a good concordance between FNAC and surgical biopsies. Therefore a FNAC should be carried out when malignancy is suspected in pediatric patients with a TN.
author	Grob,Francisca Carrillo,Diego Martínez-Aguayo,Alejandro Zoroquain,Pablo Solar,Antonieta Nicolaides,Irini González,Hernán
author_facet	Grob,Francisca Carrillo,Diego Martínez-Aguayo,Alejandro Zoroquain,Pablo Solar,Antonieta Nicolaides,Irini González,Hernán
author_sort	Grob,Francisca
title	Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
title_short	Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
title_full	Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
title_fullStr	Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
title_full_unstemmed	Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
title_sort	concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000300007
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Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría

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