Estenosis subglótica y granulomatosis con poliangeítis (Wegener) en dos casos: Report of two cases

Granulomatosis with polyangiitis (GPA) or Wegener's disease is characterized by a granulomatous vasculitis of the upper and lower airways and kidney. It involves the lower respiratory tract causing subglottic tracheal stenosis, which occurs in approximately 22% of patients. We report two female...

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Autores principales: Massa,María, Emery,Nicholas C, Bosio,Martín, Finn,Bárbara C, Bruetman,Julio E, Young,Pablo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000300014
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Sumario:Granulomatosis with polyangiitis (GPA) or Wegener's disease is characterized by a granulomatous vasculitis of the upper and lower airways and kidney. It involves the lower respiratory tract causing subglottic tracheal stenosis, which occurs in approximately 22% of patients. We report two females aged 40 and 52 years, admitted to the hospital with a subglottic tracheal stenosis. Their symptoms and management are reviewed. The frst patient responded to rituximab. The second patient required a tracheostomy.