Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos

Background: The prevalence of atopy in asthmatic children is widely variable around the world as demonstrated by large multicentric international studies. Aim: To determine the prevalence of atopy, defined as a positive reaction to one or more allergens in the skin prick test (SPT), in children with...

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Autores principales:	Mallol,Javier, Raby,Pablo, Cambiazo,David, Peñaloza,César, Palma,Ricardo, De Orúe,Manuel
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Asthma Child Epidemiology Hypersensitivity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000500003
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spelling	oai:scielo:S0034-988720140005000032014-10-10Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casosMallol,JavierRaby,PabloCambiazo,DavidPeñaloza,CésarPalma,RicardoDe Orúe,Manuel Asthma Child Epidemiology Hypersensitivity Background: The prevalence of atopy in asthmatic children is widely variable around the world as demonstrated by large multicentric international studies. Aim: To determine the prevalence of atopy, defined as a positive reaction to one or more allergens in the skin prick test (SPT), in children with persistent asthma. Material and Methods: We studied 1,199 children (54% male), aged between 4 and 16 years with confirmed diagnosis of asthma and followed at a Department of Pediatric Respiratory Medicine, between 2006 and 2011. SPT was performed according to international recommendations using standardized aeroallergens, in the forearm. A positive reaction was defined as a wheal ≥ 3 mm to one or more allergens. Results: The overall prevalence of atopy (positive SPT) was 49.4% (95% confidence interval (CI) 46.5-52.2) and there was a significant trend towards a higher prevalence with increasing age (p < 0.01). The main allergens with positive reactions were Dermatophagoides with 24.9% (95% CI 26.7-31.9), grass 24.0% (95% CI 21.6-26.5), weeds 19.0% (95% CI 16.9-21.4), cat 17.7% (95% CI 15.4-20.2), and Alternaria with 11.0% (95% CI 9.1-13.1). Sixty five percent of positive children reacted to one or more allergens. There were no adverse reactions. Conclusions: In the southern metropolitan area of Santiago de Chile, half of children with asthma are sensitized to common aeroallergens.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.5 20142014-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000500003es10.4067/S0034-98872014000500003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Asthma Child Epidemiology Hypersensitivity
spellingShingle	Asthma Child Epidemiology Hypersensitivity Mallol,Javier Raby,Pablo Cambiazo,David Peñaloza,César Palma,Ricardo De Orúe,Manuel Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
description	Background: The prevalence of atopy in asthmatic children is widely variable around the world as demonstrated by large multicentric international studies. Aim: To determine the prevalence of atopy, defined as a positive reaction to one or more allergens in the skin prick test (SPT), in children with persistent asthma. Material and Methods: We studied 1,199 children (54% male), aged between 4 and 16 years with confirmed diagnosis of asthma and followed at a Department of Pediatric Respiratory Medicine, between 2006 and 2011. SPT was performed according to international recommendations using standardized aeroallergens, in the forearm. A positive reaction was defined as a wheal ≥ 3 mm to one or more allergens. Results: The overall prevalence of atopy (positive SPT) was 49.4% (95% confidence interval (CI) 46.5-52.2) and there was a significant trend towards a higher prevalence with increasing age (p < 0.01). The main allergens with positive reactions were Dermatophagoides with 24.9% (95% CI 26.7-31.9), grass 24.0% (95% CI 21.6-26.5), weeds 19.0% (95% CI 16.9-21.4), cat 17.7% (95% CI 15.4-20.2), and Alternaria with 11.0% (95% CI 9.1-13.1). Sixty five percent of positive children reacted to one or more allergens. There were no adverse reactions. Conclusions: In the southern metropolitan area of Santiago de Chile, half of children with asthma are sensitized to common aeroallergens.
author	Mallol,Javier Raby,Pablo Cambiazo,David Peñaloza,César Palma,Ricardo De Orúe,Manuel
author_facet	Mallol,Javier Raby,Pablo Cambiazo,David Peñaloza,César Palma,Ricardo De Orúe,Manuel
author_sort	Mallol,Javier
title	Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
title_short	Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
title_full	Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
title_fullStr	Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
title_full_unstemmed	Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
title_sort	prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000500003
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Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos

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