Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna

Background: Respiratory viral infections (RVi) can be associated with a wide range of clinical manifestations. Aim: To investigate the frequency and clinical manifestations of RVi among adult patients during winter hospitalizations. Patients and Methods: All patients admitted to the hospital with fl...

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Autores principales: Riquelme,Raúl, Rioseco,María Luisa, Agüero,Yasna, Ubilla,Daniela, Mechsner,Pamela, Inzunza,Carlos, Riquelme,Mauricio
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000600002
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spelling oai:scielo:S0034-988720140006000022014-11-06Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina InternaRiquelme,RaúlRioseco,María LuisaAgüero,YasnaUbilla,DanielaMechsner,PamelaInzunza,CarlosRiquelme,Mauricio influenza Human Pneumonia Respiratory Tract Infections Respiratory Syncytial Virus Infections Viral Background: Respiratory viral infections (RVi) can be associated with a wide range of clinical manifestations. Aim: To investigate the frequency and clinical manifestations of RVi among adult patients during winter hospitalizations. Patients and Methods: All patients admitted to the hospital with flu like disease and those with fever or exacerbation of any underlying disease during hospitalization without an evident cause, were prospectively enrolled. A direct immunofluorescence (DIF) of nasopharyngeal aspirate for influenza A (IA) and B, parainfluenza 1, 2 and 3, adenovirus, respiratory syncytial virus (RSV) and metapneumovirus, was performed. Epidemiological and clinical data were recorded. Results: Between May and September 2012, 975 adults were admitted to the Internal Medicine Unit of Puerto Montt Hospital and in 128 (13%) patients, DIF was carried out. DIF was positive in 44 patients (34%) aged 65 ± 20 years, 68.2% females, corresponding to 4.5% of total hospitalizations. Eighty six percent of the latter had at least one co-morbidity, mainly asthma and chronic respiratory diseases in 34.1%, diabetes in 29.5%, cardiac problems in 25% and congestive heart failure in 20.5%. The most common RVi were RSV (n = 21, 48%) and IA (n = 17, 39%). Six patients had a nosocomial RVi. Patients infected with IA had a significantly higher frequency of fever and bronchial hyper reactivity than those infected with RSV. RVi were associated with exacerbation of underlying disease in 62% of cases and pneumonia in 27%. Two patients had a viral pericarditis. Conclusions: RVi are an important cause of adult morbidity and their detection should be routine in adult patients hospitalized during winter.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.6 20142014-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000600002es10.4067/S0034-98872014000600002
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic influenza
Human
Pneumonia
Respiratory Tract Infections
Respiratory Syncytial Virus Infections
Viral
spellingShingle influenza
Human
Pneumonia
Respiratory Tract Infections
Respiratory Syncytial Virus Infections
Viral
Riquelme,Raúl
Rioseco,María Luisa
Agüero,Yasna
Ubilla,Daniela
Mechsner,Pamela
Inzunza,Carlos
Riquelme,Mauricio
Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna
description Background: Respiratory viral infections (RVi) can be associated with a wide range of clinical manifestations. Aim: To investigate the frequency and clinical manifestations of RVi among adult patients during winter hospitalizations. Patients and Methods: All patients admitted to the hospital with flu like disease and those with fever or exacerbation of any underlying disease during hospitalization without an evident cause, were prospectively enrolled. A direct immunofluorescence (DIF) of nasopharyngeal aspirate for influenza A (IA) and B, parainfluenza 1, 2 and 3, adenovirus, respiratory syncytial virus (RSV) and metapneumovirus, was performed. Epidemiological and clinical data were recorded. Results: Between May and September 2012, 975 adults were admitted to the Internal Medicine Unit of Puerto Montt Hospital and in 128 (13%) patients, DIF was carried out. DIF was positive in 44 patients (34%) aged 65 ± 20 years, 68.2% females, corresponding to 4.5% of total hospitalizations. Eighty six percent of the latter had at least one co-morbidity, mainly asthma and chronic respiratory diseases in 34.1%, diabetes in 29.5%, cardiac problems in 25% and congestive heart failure in 20.5%. The most common RVi were RSV (n = 21, 48%) and IA (n = 17, 39%). Six patients had a nosocomial RVi. Patients infected with IA had a significantly higher frequency of fever and bronchial hyper reactivity than those infected with RSV. RVi were associated with exacerbation of underlying disease in 62% of cases and pneumonia in 27%. Two patients had a viral pericarditis. Conclusions: RVi are an important cause of adult morbidity and their detection should be routine in adult patients hospitalized during winter.
author Riquelme,Raúl
Rioseco,María Luisa
Agüero,Yasna
Ubilla,Daniela
Mechsner,Pamela
Inzunza,Carlos
Riquelme,Mauricio
author_facet Riquelme,Raúl
Rioseco,María Luisa
Agüero,Yasna
Ubilla,Daniela
Mechsner,Pamela
Inzunza,Carlos
Riquelme,Mauricio
author_sort Riquelme,Raúl
title Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna
title_short Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna
title_full Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna
title_fullStr Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna
title_full_unstemmed Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna
title_sort infección por virus respiratorios en adultos hospitalizados en un servicio de medicina interna
publisher Sociedad Médica de Santiago
publishDate 2014
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000600002
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