Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos

Retroperitoneal fibrosis (RPF) is uncommon. Eight percent of cases are associated with malignancies. The pathogenesis of cancer related RPF (MRPF) is unknown. It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action of cytokines secre...

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Autores principales:	Vega,Jorge, Ceriani,Alejandro, Jensen,Daniela
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Neoplasms Retroperitoneal fibrosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000600015
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spelling	oai:scielo:S0034-988720140006000152014-11-06Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicosVega,JorgeCeriani,AlejandroJensen,Daniela Neoplasms Retroperitoneal fibrosis Retroperitoneal fibrosis (RPF) is uncommon. Eight percent of cases are associated with malignancies. The pathogenesis of cancer related RPF (MRPF) is unknown. It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action of cytokines secreted by the tumor or a reactive inflammation. MRPF may also be a consequence of antineoplastic therapy (surgery, radiotherapy and chemotherapy). We report eight cases of MRPF associated with breast, cervix, thyroid, kidney and retroperitoneal cancer. In four patients, retroperitoneal tissue biopsy was performed, showing the typical findings of idiopathic RPF. In 6 patients MRPF appeared one to 15 years after cancer diagnosis and in two, it appeared simultaneously. The clinical presentation, course and therapeutic response are described. Six patients were treated with steroids alone and five with steroids associated with colchicine.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.6 20142014-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000600015es10.4067/S0034-98872014000600015
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Neoplasms Retroperitoneal fibrosis
spellingShingle	Neoplasms Retroperitoneal fibrosis Vega,Jorge Ceriani,Alejandro Jensen,Daniela Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos
description	Retroperitoneal fibrosis (RPF) is uncommon. Eight percent of cases are associated with malignancies. The pathogenesis of cancer related RPF (MRPF) is unknown. It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action of cytokines secreted by the tumor or a reactive inflammation. MRPF may also be a consequence of antineoplastic therapy (surgery, radiotherapy and chemotherapy). We report eight cases of MRPF associated with breast, cervix, thyroid, kidney and retroperitoneal cancer. In four patients, retroperitoneal tissue biopsy was performed, showing the typical findings of idiopathic RPF. In 6 patients MRPF appeared one to 15 years after cancer diagnosis and in two, it appeared simultaneously. The clinical presentation, course and therapeutic response are described. Six patients were treated with steroids alone and five with steroids associated with colchicine.
author	Vega,Jorge Ceriani,Alejandro Jensen,Daniela
author_facet	Vega,Jorge Ceriani,Alejandro Jensen,Daniela
author_sort	Vega,Jorge
title	Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos
title_short	Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos
title_full	Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos
title_fullStr	Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos
title_full_unstemmed	Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos
title_sort	fibrosis retroperitoneal asociada a neoplasias malignas: serie de casos clínicos
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000600015
work_keys_str_mv	AT vegajorge fibrosisretroperitonealasociadaaneoplasiasmalignasseriedecasosclinicos AT cerianialejandro fibrosisretroperitonealasociadaaneoplasiasmalignasseriedecasosclinicos AT jensendaniela fibrosisretroperitonealasociadaaneoplasiasmalignasseriedecasosclinicos
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Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos

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