Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos

Background: Despite the importance of notifying and preventing adverse drug reactions (ADRs), they are under reported and their consequences are not adequately evaluated. Aim: To assess the impact of a pharmacovigilance system carried out by a pharmacist. Material and Methods: In an internal medicin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sánchez,Ignacio, Amador,Cristián, Plaza,José Cristian, Correa,Gonzalo, Amador,Roberto
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Drug-related side effects and adverse reactions Pharmacists Pharmoacovigilance
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000800007
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872014000800007
record_format	dspace
spelling	oai:scielo:S0034-988720140008000072014-12-12Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentosSánchez,IgnacioAmador,CristiánPlaza,José CristianCorrea,GonzaloAmador,Roberto Drug-related side effects and adverse reactions Pharmacists Pharmoacovigilance Background: Despite the importance of notifying and preventing adverse drug reactions (ADRs), they are under reported and their consequences are not adequately evaluated. Aim: To assess the impact of a pharmacovigilance system carried out by a pharmacist. Material and Methods: In an internal medicine service, the spontaneous report of ADRs was compared blindly with an active pharmacovigilance system in which a pharmacist detected, monitored and prevented ADRs. Results: A total of 1,196 patients was included. Of these 604 were hospitalized in intervened wards, where 50 suspected ADRs in 47 patients were reported. In non-intervened wards, only three ADRs were spontaneously reported. Therefore, the pharmacovigilance system significantly improved the detection and report of ADRs with a risk ratio of 15.4 (95% confidence intervals 4.8-49.1). Sixty six percent of ADRs were classified as severe. Antimicrobials were the main group of medications causing ADRs in 44% of reports. Forty three percent of ADRs were preventable and prolonged hospital stay by a mean of eight days. Conclusions: An active pharmacovigilance system carried out by pharmacists improves the detection of ADRs and promotes its prevention.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.8 20142014-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000800007es10.4067/S0034-98872014000800007
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Drug-related side effects and adverse reactions Pharmacists Pharmoacovigilance
spellingShingle	Drug-related side effects and adverse reactions Pharmacists Pharmoacovigilance Sánchez,Ignacio Amador,Cristián Plaza,José Cristian Correa,Gonzalo Amador,Roberto Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
description	Background: Despite the importance of notifying and preventing adverse drug reactions (ADRs), they are under reported and their consequences are not adequately evaluated. Aim: To assess the impact of a pharmacovigilance system carried out by a pharmacist. Material and Methods: In an internal medicine service, the spontaneous report of ADRs was compared blindly with an active pharmacovigilance system in which a pharmacist detected, monitored and prevented ADRs. Results: A total of 1,196 patients was included. Of these 604 were hospitalized in intervened wards, where 50 suspected ADRs in 47 patients were reported. In non-intervened wards, only three ADRs were spontaneously reported. Therefore, the pharmacovigilance system significantly improved the detection and report of ADRs with a risk ratio of 15.4 (95% confidence intervals 4.8-49.1). Sixty six percent of ADRs were classified as severe. Antimicrobials were the main group of medications causing ADRs in 44% of reports. Forty three percent of ADRs were preventable and prolonged hospital stay by a mean of eight days. Conclusions: An active pharmacovigilance system carried out by pharmacists improves the detection of ADRs and promotes its prevention.
author	Sánchez,Ignacio Amador,Cristián Plaza,José Cristian Correa,Gonzalo Amador,Roberto
author_facet	Sánchez,Ignacio Amador,Cristián Plaza,José Cristian Correa,Gonzalo Amador,Roberto
author_sort	Sánchez,Ignacio
title	Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
title_short	Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
title_full	Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
title_fullStr	Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
title_full_unstemmed	Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
title_sort	impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000800007
work_keys_str_mv	AT sanchezignacio impactoclinicodeunsistemadefarmacovigilanciaactivarealizadoporunfarmaceuticoenelreporteysubnotificaciondereaccionesadversasamedicamentos AT amadorcristian impactoclinicodeunsistemadefarmacovigilanciaactivarealizadoporunfarmaceuticoenelreporteysubnotificaciondereaccionesadversasamedicamentos AT plazajosecristian impactoclinicodeunsistemadefarmacovigilanciaactivarealizadoporunfarmaceuticoenelreporteysubnotificaciondereaccionesadversasamedicamentos AT correagonzalo impactoclinicodeunsistemadefarmacovigilanciaactivarealizadoporunfarmaceuticoenelreporteysubnotificaciondereaccionesadversasamedicamentos AT amadorroberto impactoclinicodeunsistemadefarmacovigilanciaactivarealizadoporunfarmaceuticoenelreporteysubnotificaciondereaccionesadversasamedicamentos
_version_	1718436771209936896

Impacto clínico de un sistema de farmacovigilancia activa realizado por un farmacéutico en el reporte y subnotificación de reacciones adversas a medicamentos

Ejemplares similares