Enfermedad inflamatoria intestinal a partir de una experiencia local

Background: The incidence and prevalence of Inflammatory Bowel Disease (IBD) has increased. Aim: To determine demographic and clinical characteristics of patients with IBD in a Chilean private hospital. Patients and Methods: Review of a prospective registry of patients with IBD, started on 2012. It...

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Autores principales: Simian,Daniela, Estay,Camila, Lubascher,Jaime, Acuña,Raúl, Kronberg,Udo, Figueroa,Carolina, Brahm,Javier, Silva,Guillermo, López-Köstner,Francisco, Wainstein,Claudio, Larach,Andrés, Larach,Jorge, Quera,Rodrigo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000800008
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spelling oai:scielo:S0034-988720140008000082014-12-12Enfermedad inflamatoria intestinal a partir de una experiencia localSimian,DanielaEstay,CamilaLubascher,JaimeAcuña,RaúlKronberg,UdoFigueroa,CarolinaBrahm,JavierSilva,GuillermoLópez-Köstner,FranciscoWainstein,ClaudioLarach,AndrésLarach,JorgeQuera,Rodrigo Colitis Ulcerative Crohn Disease Inflammatory Bowel Disease Trends Background: The incidence and prevalence of Inflammatory Bowel Disease (IBD) has increased. Aim: To determine demographic and clinical characteristics of patients with IBD in a Chilean private hospital. Patients and Methods: Review of a prospective registry of patients with IBD, started on 2012. It includes clinical, imaging, endoscopical and pathological information of patients. Results: Data of 316 patients with IBD, aged 16 to 86 years (56% females), were analyzed. Ulcerative Colitis (UC), Crohn´s and non-classifiable IBD were diagnosed in 230, 77 and 9 patients, respectively. The disease was diagnosed in 82% of patients in the period between 2002 and 2012. There was a peak in the diagnosis of both UC and CD between 20 and 39 years of age, without gender differences. The disease switched from UC to CD in six patients. In four, there was a change in disease behavior. Thirty eight patients were treated with biological therapy. The median lapse between the diagnosis and the use of biological therapy was 1 year in patients diagnosed after 2007, compared with 5.5 years among those patients diagnosed before 2007 (p = 0.001). There was a trend towards a higher requirement of surgery until 2006. Subsequently there was a stabilization of the requirement, concomitant with the incorporation of biological therapy. Conclusions: An adequate registry of IBD patients is necessary to improve demographic and clinical characteristics. A national registry is needed to assess the epidemiological changes of IBD in Chile.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.8 20142014-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000800008es10.4067/S0034-98872014000800008
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Colitis Ulcerative
Crohn Disease
Inflammatory Bowel Disease
Trends
spellingShingle Colitis Ulcerative
Crohn Disease
Inflammatory Bowel Disease
Trends
Simian,Daniela
Estay,Camila
Lubascher,Jaime
Acuña,Raúl
Kronberg,Udo
Figueroa,Carolina
Brahm,Javier
Silva,Guillermo
López-Köstner,Francisco
Wainstein,Claudio
Larach,Andrés
Larach,Jorge
Quera,Rodrigo
Enfermedad inflamatoria intestinal a partir de una experiencia local
description Background: The incidence and prevalence of Inflammatory Bowel Disease (IBD) has increased. Aim: To determine demographic and clinical characteristics of patients with IBD in a Chilean private hospital. Patients and Methods: Review of a prospective registry of patients with IBD, started on 2012. It includes clinical, imaging, endoscopical and pathological information of patients. Results: Data of 316 patients with IBD, aged 16 to 86 years (56% females), were analyzed. Ulcerative Colitis (UC), Crohn´s and non-classifiable IBD were diagnosed in 230, 77 and 9 patients, respectively. The disease was diagnosed in 82% of patients in the period between 2002 and 2012. There was a peak in the diagnosis of both UC and CD between 20 and 39 years of age, without gender differences. The disease switched from UC to CD in six patients. In four, there was a change in disease behavior. Thirty eight patients were treated with biological therapy. The median lapse between the diagnosis and the use of biological therapy was 1 year in patients diagnosed after 2007, compared with 5.5 years among those patients diagnosed before 2007 (p = 0.001). There was a trend towards a higher requirement of surgery until 2006. Subsequently there was a stabilization of the requirement, concomitant with the incorporation of biological therapy. Conclusions: An adequate registry of IBD patients is necessary to improve demographic and clinical characteristics. A national registry is needed to assess the epidemiological changes of IBD in Chile.
author Simian,Daniela
Estay,Camila
Lubascher,Jaime
Acuña,Raúl
Kronberg,Udo
Figueroa,Carolina
Brahm,Javier
Silva,Guillermo
López-Köstner,Francisco
Wainstein,Claudio
Larach,Andrés
Larach,Jorge
Quera,Rodrigo
author_facet Simian,Daniela
Estay,Camila
Lubascher,Jaime
Acuña,Raúl
Kronberg,Udo
Figueroa,Carolina
Brahm,Javier
Silva,Guillermo
López-Köstner,Francisco
Wainstein,Claudio
Larach,Andrés
Larach,Jorge
Quera,Rodrigo
author_sort Simian,Daniela
title Enfermedad inflamatoria intestinal a partir de una experiencia local
title_short Enfermedad inflamatoria intestinal a partir de una experiencia local
title_full Enfermedad inflamatoria intestinal a partir de una experiencia local
title_fullStr Enfermedad inflamatoria intestinal a partir de una experiencia local
title_full_unstemmed Enfermedad inflamatoria intestinal a partir de una experiencia local
title_sort enfermedad inflamatoria intestinal a partir de una experiencia local
publisher Sociedad Médica de Santiago
publishDate 2014
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000800008
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