Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento

The discovery of the renin-angiotensin-aldosterone system (RAS) was one of the important findings in physiology. Two research groups, in both North and South America, independently discovered that renin released a novel vasopressor agent. The Argentine group named it hypertensin, and called hyperten...

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Autores principales: Cherne,Pablo Nicolás, Young,Pablo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000900017
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spelling oai:scielo:S0034-988720140009000172014-12-17Historia del sistema renina angiotensina: grandes hombres, un gran descubrimientoCherne,Pablo NicolásYoung,Pablo Angiotensin History of medicine Kidney Physiology The discovery of the renin-angiotensin-aldosterone system (RAS) was one of the important findings in physiology. Two research groups, in both North and South America, independently discovered that renin released a novel vasopressor agent. The Argentine group named it hypertensin, and called hypertensinogen to its plasma protein substrate. The group from the United States named it angiotonin. In 1958, Braun Menendez and Irvine Page suggested that the peptide´s name should be angiotensin. Development of angiotensin converting enzyme (ACE) inhibitors proved that the RAS is effective in controlling hypertension and heart failure, and in preventing vascular injury in chronic diseases. Both teams, showing that beyond being great investigators they were remarkable persons, shared the merit of the discovery.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.9 20142014-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000900017es10.4067/S0034-98872014000900017
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Angiotensin
History of medicine
Kidney
Physiology
spellingShingle Angiotensin
History of medicine
Kidney
Physiology
Cherne,Pablo Nicolás
Young,Pablo
Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
description The discovery of the renin-angiotensin-aldosterone system (RAS) was one of the important findings in physiology. Two research groups, in both North and South America, independently discovered that renin released a novel vasopressor agent. The Argentine group named it hypertensin, and called hypertensinogen to its plasma protein substrate. The group from the United States named it angiotonin. In 1958, Braun Menendez and Irvine Page suggested that the peptide´s name should be angiotensin. Development of angiotensin converting enzyme (ACE) inhibitors proved that the RAS is effective in controlling hypertension and heart failure, and in preventing vascular injury in chronic diseases. Both teams, showing that beyond being great investigators they were remarkable persons, shared the merit of the discovery.
author Cherne,Pablo Nicolás
Young,Pablo
author_facet Cherne,Pablo Nicolás
Young,Pablo
author_sort Cherne,Pablo Nicolás
title Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
title_short Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
title_full Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
title_fullStr Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
title_full_unstemmed Historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
title_sort historia del sistema renina angiotensina: grandes hombres, un gran descubrimiento
publisher Sociedad Médica de Santiago
publishDate 2014
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014000900017
work_keys_str_mv AT chernepablonicolas historiadelsistemareninaangiotensinagrandeshombresungrandescubrimiento
AT youngpablo historiadelsistemareninaangiotensinagrandeshombresungrandescubrimiento
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