Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol

Human fascioliasis is a parasitic zoonosis that affects the liver of human and herbivorous animals. In chronic cases, its diagnosis is confirmed by direct visualization of parasitic eggs in stool examination, by positive testing for Fasciola hepatica antigens in stools, or by direct observation of p...

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Autores principales:	Gil,Luis Carlos, Díaz,Alex, Rueda,Carlos, Martínez,Christian, Castillo,Douglas, Apt,Werner
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Cholangiography Fasciola hepatica Triclabendazole
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001000014
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spelling	oai:scielo:S0034-988720140010000142015-01-15Fascioliasis hepática humana: resistencia al tratamiento con triclabendazolGil,Luis CarlosDíaz,AlexRueda,CarlosMartínez,ChristianCastillo,DouglasApt,Werner Cholangiography Fasciola hepatica Triclabendazole Human fascioliasis is a parasitic zoonosis that affects the liver of human and herbivorous animals. In chronic cases, its diagnosis is confirmed by direct visualization of parasitic eggs in stool examination, by positive testing for Fasciola hepatica antigens in stools, or by direct observation of parasites by endoscopic retrograde cholangiography or surgery. In acute cases, serological reactions as immunoblothing or detection of parasite antigens in the blood are useful. The treatment of choice is triclabendazole. However, parasite resistance in animals, as well as in man, has been reported to this drug. We report four patients in whom the parasitic infection persisted despite a course of treatment with triclabendazole.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.10 20142014-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001000014es10.4067/S0034-98872014001000014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cholangiography Fasciola hepatica Triclabendazole
spellingShingle	Cholangiography Fasciola hepatica Triclabendazole Gil,Luis Carlos Díaz,Alex Rueda,Carlos Martínez,Christian Castillo,Douglas Apt,Werner Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
description	Human fascioliasis is a parasitic zoonosis that affects the liver of human and herbivorous animals. In chronic cases, its diagnosis is confirmed by direct visualization of parasitic eggs in stool examination, by positive testing for Fasciola hepatica antigens in stools, or by direct observation of parasites by endoscopic retrograde cholangiography or surgery. In acute cases, serological reactions as immunoblothing or detection of parasite antigens in the blood are useful. The treatment of choice is triclabendazole. However, parasite resistance in animals, as well as in man, has been reported to this drug. We report four patients in whom the parasitic infection persisted despite a course of treatment with triclabendazole.
author	Gil,Luis Carlos Díaz,Alex Rueda,Carlos Martínez,Christian Castillo,Douglas Apt,Werner
author_facet	Gil,Luis Carlos Díaz,Alex Rueda,Carlos Martínez,Christian Castillo,Douglas Apt,Werner
author_sort	Gil,Luis Carlos
title	Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
title_short	Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
title_full	Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
title_fullStr	Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
title_full_unstemmed	Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
title_sort	fascioliasis hepática humana: resistencia al tratamiento con triclabendazol
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001000014
work_keys_str_mv	AT gilluiscarlos fascioliasishepaticahumanaresistenciaaltratamientocontriclabendazol AT diazalex fascioliasishepaticahumanaresistenciaaltratamientocontriclabendazol AT ruedacarlos fascioliasishepaticahumanaresistenciaaltratamientocontriclabendazol AT martinezchristian fascioliasishepaticahumanaresistenciaaltratamientocontriclabendazol AT castillodouglas fascioliasishepaticahumanaresistenciaaltratamientocontriclabendazol AT aptwerner fascioliasishepaticahumanaresistenciaaltratamientocontriclabendazol
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Fascioliasis hepática humana: resistencia al tratamiento con triclabendazol

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