Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas

Background: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors for congenital malformations. Patients and Methods: Retrospective case-contro...

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Autores principales:	Canals C,Andrea, Cavada C,Gabriel, Nazer H,Julio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Congenital abnormalities Risk factors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001100010
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spelling	oai:scielo:S0034-988720140011000102015-02-18Factores de riesgo de ocurrencia y gravedad de malformaciones congénitasCanals C,AndreaCavada C,GabrielNazer H,Julio Congenital abnormalities Risk factors Background: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors for congenital malformations. Patients and Methods: Retrospective case-control study of births registered in the database of The Latin American Collaborative Study of Congenital Malformations (ECLAMC), in the period 2001-2010. Results: Birth weight and gestational age were significantly lower in cases than controls, behaving as risk factors and associated with a greater severity of congenital malformations. The risk and severity of congenital malformations increased along with mother’s age. Fetal growth retardation, a history of congenital malformations in the family, physical factors and acute illnesses of the mother in the first trimester of pregnancy were also significant risk factors for congenital malformations and their severity. The educational level of the mother was a protective factor for congenital malformations and their severity. Conclusions: Variables previously identified as risk factors for congenital malformations, were significantly related with the occurrence of congenital malformations and their severity.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.11 20142014-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001100010es10.4067/S0034-98872014001100010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Congenital abnormalities Risk factors
spellingShingle	Congenital abnormalities Risk factors Canals C,Andrea Cavada C,Gabriel Nazer H,Julio Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
description	Background: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality. Aim: To identify risk factors for congenital malformations. Patients and Methods: Retrospective case-control study of births registered in the database of The Latin American Collaborative Study of Congenital Malformations (ECLAMC), in the period 2001-2010. Results: Birth weight and gestational age were significantly lower in cases than controls, behaving as risk factors and associated with a greater severity of congenital malformations. The risk and severity of congenital malformations increased along with mother’s age. Fetal growth retardation, a history of congenital malformations in the family, physical factors and acute illnesses of the mother in the first trimester of pregnancy were also significant risk factors for congenital malformations and their severity. The educational level of the mother was a protective factor for congenital malformations and their severity. Conclusions: Variables previously identified as risk factors for congenital malformations, were significantly related with the occurrence of congenital malformations and their severity.
author	Canals C,Andrea Cavada C,Gabriel Nazer H,Julio
author_facet	Canals C,Andrea Cavada C,Gabriel Nazer H,Julio
author_sort	Canals C,Andrea
title	Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
title_short	Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
title_full	Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
title_fullStr	Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
title_full_unstemmed	Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
title_sort	factores de riesgo de ocurrencia y gravedad de malformaciones congénitas
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001100010
work_keys_str_mv	AT canalscandrea factoresderiesgodeocurrenciaygravedaddemalformacionescongenitas AT cavadacgabriel factoresderiesgodeocurrenciaygravedaddemalformacionescongenitas AT nazerhjulio factoresderiesgodeocurrenciaygravedaddemalformacionescongenitas
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Factores de riesgo de ocurrencia y gravedad de malformaciones congénitas

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