Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014

Background: Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. Aim: To report our experience with THA in patients with multiple myeloma. Material and Methods: Retrospectiv...

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Autores principales: Sarmiento,Mauricio, Lira,Pablo, Ocqueteau,Mauricio, Rodríguez,María Alejandra, García,María José, Jara,Verónica, Bertín,Pablo, Ramírez,Pablo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200001
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spelling oai:scielo:S0034-988720140012000012015-02-19Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014Sarmiento,MauricioLira,PabloOcqueteau,MauricioRodríguez,María AlejandraGarcía,María JoséJara,VerónicaBertín,PabloRamírez,Pablo Amyloidosis Hematopoietic stem cell transplantation Multiple myeloma Background: Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. Aim: To report our experience with THA in patients with multiple myeloma. Material and Methods: Retrospective review of the hematopoietic cell transplantation database of a hospital of a Medical School. Forty seven patients with multiple myeloma and six with amyloid light chain amyloidosis were identified. Clinical and demographic data were obtained from the records. Results: The overall five year survival of patients was 55%. Transplant-related or non-relapse mortality occurred in 7%. We found no differences in outcomes among patients younger or older than 50 years. Conclusions: Our data supports that THA can be done in our country with similar results to those obtained in international transplantation centers. Chronological age should not be a limitation to offer this therapy to patients with multiple myeloma and amyloidosis.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.12 20142014-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200001es10.4067/S0034-98872014001200001
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Amyloidosis
Hematopoietic stem cell transplantation
Multiple myeloma
spellingShingle Amyloidosis
Hematopoietic stem cell transplantation
Multiple myeloma
Sarmiento,Mauricio
Lira,Pablo
Ocqueteau,Mauricio
Rodríguez,María Alejandra
García,María José
Jara,Verónica
Bertín,Pablo
Ramírez,Pablo
Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
description Background: Autologous hematopoietic cell transplantation (THA) in patients with multiple myeloma and amyloidosis is the standard of care to promote disease free survival and quality of life. Aim: To report our experience with THA in patients with multiple myeloma. Material and Methods: Retrospective review of the hematopoietic cell transplantation database of a hospital of a Medical School. Forty seven patients with multiple myeloma and six with amyloid light chain amyloidosis were identified. Clinical and demographic data were obtained from the records. Results: The overall five year survival of patients was 55%. Transplant-related or non-relapse mortality occurred in 7%. We found no differences in outcomes among patients younger or older than 50 years. Conclusions: Our data supports that THA can be done in our country with similar results to those obtained in international transplantation centers. Chronological age should not be a limitation to offer this therapy to patients with multiple myeloma and amyloidosis.
author Sarmiento,Mauricio
Lira,Pablo
Ocqueteau,Mauricio
Rodríguez,María Alejandra
García,María José
Jara,Verónica
Bertín,Pablo
Ramírez,Pablo
author_facet Sarmiento,Mauricio
Lira,Pablo
Ocqueteau,Mauricio
Rodríguez,María Alejandra
García,María José
Jara,Verónica
Bertín,Pablo
Ramírez,Pablo
author_sort Sarmiento,Mauricio
title Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
title_short Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
title_full Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
title_fullStr Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
title_full_unstemmed Experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
title_sort experiencia de 22 años de trasplante autólogo de células hematopoyéticas en pacientes con mieloma múltiple o amiloidosis sistémica. 1992-2014
publisher Sociedad Médica de Santiago
publishDate 2014
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200001
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