Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias

Background: The detection of anti-transglutaminase IgA (tTG) and anti-endomysial (EMA) is used for screening of celiac disease (CD) with a sensitivity and specificity of 90 and 99% respectively. There is an association between CD and connective tissue diseases (CTD). Aim: To report the frequency of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rodríguez,Graciela Rita, Zazzetti,Federico, da Representaçao,Silvia Raquel, Lencina,María Verónica, Barreira,Juan Carlos, Álvarez,Karina Elizabeth
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2014
Materias:	Autoimmunity Celiac disease Connective Tissue Diseases Rheumatic Diseases
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200003
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872014001200003
record_format	dspace
spelling	oai:scielo:S0034-988720140012000032015-02-19Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatoriasRodríguez,Graciela RitaZazzetti,Federicoda Representaçao,Silvia RaquelLencina,María VerónicaBarreira,Juan CarlosÁlvarez,Karina Elizabeth Autoimmunity Celiac disease Connective Tissue Diseases Rheumatic Diseases Background: The detection of anti-transglutaminase IgA (tTG) and anti-endomysial (EMA) is used for screening of celiac disease (CD) with a sensitivity and specificity of 90 and 99% respectively. There is an association between CD and connective tissue diseases (CTD). Aim: To report the frequency of IgA tTG and EMA in patients with a definite diagnosis of CTD and inflammatory arthropathies (IA). Material and Methods: One hundred forty nine patients, aged 19 to 86 years (133 females) with CTD and IA were studied. tTG were determined by ELISA and EMA by indirect immunofluorescence. Results: Eight participants had at least one positive antibody (5.4%, confidence intervals (CI) = 1.8-9), six had both (4.0% CI = 0.9-7.2) and two had only tTG positive. An intestinal biopsy was performed in four of these participants, finding a marked villous atrophy in three and partial atrophy in one. Conclusions: Five percent of this group of patients with CTD or IA had positive antibodies for CD.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.142 n.12 20142014-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200003es10.4067/S0034-98872014001200003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Autoimmunity Celiac disease Connective Tissue Diseases Rheumatic Diseases
spellingShingle	Autoimmunity Celiac disease Connective Tissue Diseases Rheumatic Diseases Rodríguez,Graciela Rita Zazzetti,Federico da Representaçao,Silvia Raquel Lencina,María Verónica Barreira,Juan Carlos Álvarez,Karina Elizabeth Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
description	Background: The detection of anti-transglutaminase IgA (tTG) and anti-endomysial (EMA) is used for screening of celiac disease (CD) with a sensitivity and specificity of 90 and 99% respectively. There is an association between CD and connective tissue diseases (CTD). Aim: To report the frequency of IgA tTG and EMA in patients with a definite diagnosis of CTD and inflammatory arthropathies (IA). Material and Methods: One hundred forty nine patients, aged 19 to 86 years (133 females) with CTD and IA were studied. tTG were determined by ELISA and EMA by indirect immunofluorescence. Results: Eight participants had at least one positive antibody (5.4%, confidence intervals (CI) = 1.8-9), six had both (4.0% CI = 0.9-7.2) and two had only tTG positive. An intestinal biopsy was performed in four of these participants, finding a marked villous atrophy in three and partial atrophy in one. Conclusions: Five percent of this group of patients with CTD or IA had positive antibodies for CD.
author	Rodríguez,Graciela Rita Zazzetti,Federico da Representaçao,Silvia Raquel Lencina,María Verónica Barreira,Juan Carlos Álvarez,Karina Elizabeth
author_facet	Rodríguez,Graciela Rita Zazzetti,Federico da Representaçao,Silvia Raquel Lencina,María Verónica Barreira,Juan Carlos Álvarez,Karina Elizabeth
author_sort	Rodríguez,Graciela Rita
title	Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
title_short	Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
title_full	Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
title_fullStr	Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
title_full_unstemmed	Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
title_sort	frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias
publisher	Sociedad Médica de Santiago
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200003
work_keys_str_mv	AT rodriguezgracielarita frecuenciadeanticuerposparadiagnosticodeenfermedadceliacaenpacientesconenfermedadesdeltejidoconectivoyartropatiasinflamatorias AT zazzettifederico frecuenciadeanticuerposparadiagnosticodeenfermedadceliacaenpacientesconenfermedadesdeltejidoconectivoyartropatiasinflamatorias AT darepresentacaosilviaraquel frecuenciadeanticuerposparadiagnosticodeenfermedadceliacaenpacientesconenfermedadesdeltejidoconectivoyartropatiasinflamatorias AT lencinamariaveronica frecuenciadeanticuerposparadiagnosticodeenfermedadceliacaenpacientesconenfermedadesdeltejidoconectivoyartropatiasinflamatorias AT barreirajuancarlos frecuenciadeanticuerposparadiagnosticodeenfermedadceliacaenpacientesconenfermedadesdeltejidoconectivoyartropatiasinflamatorias AT alvarezkarinaelizabeth frecuenciadeanticuerposparadiagnosticodeenfermedadceliacaenpacientesconenfermedadesdeltejidoconectivoyartropatiasinflamatorias
_version_	1718436791609982976

Frecuencia de anticuerpos para diagnóstico de enfermedad celíaca en pacientes con enfermedades del tejido conectivo y artropatías inflamatorias

Ejemplares similares