Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años

Background: Guillain-Barré syndrome (GBS) is the commonest cause of acute flaccid paralysis worldwide, with an incidence of 0.6-4 per 100.000 inhabitants per year. It affects all age groups and carries an incapacity burden of up to 20%. Aim: To describe the features of GBS in adult Chilean patients...

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Autores principales:	Cea,Gabriel, Jara,Paula, Quevedo,Fernando
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2015
Materias:	Epidemiology Immunoglobulins, intravenous, plasmapheresis Guillain-Barré Syndrome
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000200005
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spelling	oai:scielo:S0034-988720150002000052015-04-09Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 añosCea,GabrielJara,PaulaQuevedo,Fernando Epidemiology Immunoglobulins, intravenous, plasmapheresis Guillain-Barré Syndrome Background: Guillain-Barré syndrome (GBS) is the commonest cause of acute flaccid paralysis worldwide, with an incidence of 0.6-4 per 100.000 inhabitants per year. It affects all age groups and carries an incapacity burden of up to 20%. Aim: To describe the features of GBS in adult Chilean patients admitted to a tertiary care hospital. Material and Methods: Review of medical records of 41 patients aged 17 to 81 years (30 males) admitted to a public hospital with the diagnosis of GBS between 2003 and 2009. According to clinical and electrophysiological criteria, the patients were classified into different varieties of GBS. Results: The incidence of GBS was higher in males (2.7:1) and the demyelinated GBS variety was found in 66% of cases. According to the Hughes disability score, patients treated with plasmapheresis, showed non-statistically significant better outcomes than those treated with intravenous immunoglobulin. Conclusions: In this group of patients the demyelinated variety of GBS was more common than the axonal type. Although not statistically significant, the better response to plasmapheresis is encouraging and should prompt a controlled study.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.143 n.2 20152015-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000200005es10.4067/S0034-98872015000200005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Epidemiology Immunoglobulins, intravenous, plasmapheresis Guillain-Barré Syndrome
spellingShingle	Epidemiology Immunoglobulins, intravenous, plasmapheresis Guillain-Barré Syndrome Cea,Gabriel Jara,Paula Quevedo,Fernando Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años
description	Background: Guillain-Barré syndrome (GBS) is the commonest cause of acute flaccid paralysis worldwide, with an incidence of 0.6-4 per 100.000 inhabitants per year. It affects all age groups and carries an incapacity burden of up to 20%. Aim: To describe the features of GBS in adult Chilean patients admitted to a tertiary care hospital. Material and Methods: Review of medical records of 41 patients aged 17 to 81 years (30 males) admitted to a public hospital with the diagnosis of GBS between 2003 and 2009. According to clinical and electrophysiological criteria, the patients were classified into different varieties of GBS. Results: The incidence of GBS was higher in males (2.7:1) and the demyelinated GBS variety was found in 66% of cases. According to the Hughes disability score, patients treated with plasmapheresis, showed non-statistically significant better outcomes than those treated with intravenous immunoglobulin. Conclusions: In this group of patients the demyelinated variety of GBS was more common than the axonal type. Although not statistically significant, the better response to plasmapheresis is encouraging and should prompt a controlled study.
author	Cea,Gabriel Jara,Paula Quevedo,Fernando
author_facet	Cea,Gabriel Jara,Paula Quevedo,Fernando
author_sort	Cea,Gabriel
title	Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años
title_short	Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años
title_full	Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años
title_fullStr	Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años
title_full_unstemmed	Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años
title_sort	características epidemiológicas del síndrome de guillain-barré en población chilena: estudio hospitalario en un período de 7 años
publisher	Sociedad Médica de Santiago
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872015000200005
work_keys_str_mv	AT ceagabriel caracteristicasepidemiologicasdelsindromedeguillainbarreenpoblacionchilenaestudiohospitalarioenunperiodode7anos AT jarapaula caracteristicasepidemiologicasdelsindromedeguillainbarreenpoblacionchilenaestudiohospitalarioenunperiodode7anos AT quevedofernando caracteristicasepidemiologicasdelsindromedeguillainbarreenpoblacionchilenaestudiohospitalarioenunperiodode7anos
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Características epidemiológicas del síndrome de Guillain-Barré en población chilena: estudio hospitalario en un período de 7 años

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